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The role of satellite image-processing for national-scale estimates of gene flow from genetically modified crops: Rapeseed in the UK as a model (2004)
Journal Article
Elliott, L. J., Mason, D. C., Wilkinson, M. J., Allainguillaume, J., Norris, C., Alexander, M., & Welters, R. (2004). The role of satellite image-processing for national-scale estimates of gene flow from genetically modified crops: Rapeseed in the UK as a model. Journal of Applied Ecology, 41(6), 1174-1184. https://doi.org/10.1111/j.0021-8901.2004.00963.x

1. There is concern over the possibility of unwanted environmental change following transgene movement from genetically modified (GM) rapeseed Brassica napus to its wild and weedy relatives. 2. The aim of this research was to develop a remote sensing... Read More about The role of satellite image-processing for national-scale estimates of gene flow from genetically modified crops: Rapeseed in the UK as a model.

The pig CYP2E1 promoter is activated by COUP-TF1 and HNF-1 and is inhibited by androstenone (2004)
Journal Article
Doran, E., Tambyrajah, W. S., Doran (nee Udovikova), O., Wood, J. D., & McGivan, J. D. (2004). The pig CYP2E1 promoter is activated by COUP-TF1 and HNF-1 and is inhibited by androstenone. Archives of Biochemistry and Biophysics, 431(2), 252-260. https://doi.org/10.1016/j.abb.2004.08.016

Functional analysis of the pig cytochrome P4502E1 (CYP2E1) promoter identified two major activating elements. One corresponded to the hepatic nuclear factor 1 (HNF-1) consensus binding sequence at nucleotides -128/-98 and the other was located in the... Read More about The pig CYP2E1 promoter is activated by COUP-TF1 and HNF-1 and is inhibited by androstenone.

p16INK4a polymorphism: Associations with tumour progression in patients with sporadic colorectal cancer (2004)
Journal Article
McCloud, J. M., Sivakumar, R., Greenhough, A., Elder, J., Jones, P. W., Deakin, M., …Hoban, P. R. (2004). p16INK4a polymorphism: Associations with tumour progression in patients with sporadic colorectal cancer. International Journal of Oncology, 25(5), 1447-1452. https://doi.org/10.3892/ijo.25.5.1447

Deregulated tumour expression of p16INK4a has previously been described in association with clinical progression in sporadic colorectal cancer patients (CRC). Furthermore, p16INK4a promoter hypermethylation leading to gene silencing has been shown to... Read More about p16INK4a polymorphism: Associations with tumour progression in patients with sporadic colorectal cancer.

Fundamental subchondral bone changes in spontaneous knee osteoarthritis (2004)
Journal Article
Anderson-MacKenzie, J. M., Quasnichka, H. L., Starr, R. L., Lewis, E. J., Billingham, M. E., & Bailey, A. J. (2005). Fundamental subchondral bone changes in spontaneous knee osteoarthritis. International Journal of Biochemistry and Cell Biology, 37(1), 224-236. https://doi.org/10.1016/j.biocel.2004.06.016

Osteoarthritis has an unknown aetiology, and tissue samples from early stage human osteoarthritis tissue cannot be reliably obtained. Therefore understanding the development of OA relies on using animal models: such as the spontaneous changes seen in... Read More about Fundamental subchondral bone changes in spontaneous knee osteoarthritis.

Sub-lethal effects of metal exposure: Physiological and behavioural responses of the estuarine bivalve Macoma balthica (2004)
Journal Article
Duquesne, S., Liess, M., & Bird, D. J. (2004). Sub-lethal effects of metal exposure: Physiological and behavioural responses of the estuarine bivalve Macoma balthica. Marine Environmental Research, 58(2-5), 245-250. https://doi.org/10.1016/j.marenvres.2004.03.066

Variation in glycogen concentration, condition index (CI) and filtration activity were measured in the bivalve Macoma balthica buried in sediment and experimentally exposed to cadmium (Cd). The stress due to elevated but sub-lethal concentrations (30... Read More about Sub-lethal effects of metal exposure: Physiological and behavioural responses of the estuarine bivalve Macoma balthica.

A screen-printed, amperometric, biosensor array for the detection of organophosphate pesticides based on inhibition of wild type, and mutant acetylcholinesterases, from Drosophila melanogaster (2004)
Journal Article
Hart, J. P., Crew, A. P., Hart, J. P., Wedge, R., Marty, J. L., & Fournier, D. (2004). A screen-printed, amperometric, biosensor array for the detection of organophosphate pesticides based on inhibition of wild type, and mutant acetylcholinesterases, from Drosophila melanogaster. Analytical Letters, 37(8), 1601-1610. https://doi.org/10.1081/AL-120037590

Screen-printed carbon electrodes (SPCEs) modified with cobalt phthalocyanine (CoPC) have been used as base transducers in the construction of amperometric pesticide biosensors. Six individual biosensors were fabricated by depositing wildtype (WT) ace... Read More about A screen-printed, amperometric, biosensor array for the detection of organophosphate pesticides based on inhibition of wild type, and mutant acetylcholinesterases, from Drosophila melanogaster.

Penetrative convection induced by the absorption of radiation with a nonlinear internal heat source (2004)
Journal Article
Hill, A. A. (2004). Penetrative convection induced by the absorption of radiation with a nonlinear internal heat source. Dynamics of Atmospheres and Oceans, 38(1), 57-67. https://doi.org/10.1016/j.dynatmoce.2004.03.002

A model for convection induced by the selective absorption of radiation in a fluid layer is investigated. The concentration based internal heat source is modelled quadratically. A linear analysis and conditional nonlinear analysis are performed. Due... Read More about Penetrative convection induced by the absorption of radiation with a nonlinear internal heat source.

DNA microarray screening of differential gene expression in bone marrow samples from AML, non-AML patients and AML cell lines (2004)
Journal Article
Gray, A. G., Morgan, L. M., Avent, N. D., Smith, M. A., Court, E. L., Hancock, J. T., & Smith, J. G. (2004). DNA microarray screening of differential gene expression in bone marrow samples from AML, non-AML patients and AML cell lines. Leukemia Research, 28(7), 743-753. https://doi.org/10.1016/j.leukres.2003.11.011

This study used cDNA microarray technology to compare gene expression profiles in acute myeloblastic leukaemia (AML) with cDNA dot-blot and real time PCR analysis of cDNA transcripts to confirm array data. Patient AML marrow samples and AML cell line... Read More about DNA microarray screening of differential gene expression in bone marrow samples from AML, non-AML patients and AML cell lines.

Roles for cysteine residues in the regulatory CXXC motif of human mitochondrial branched chain aminotransferase enzyme (2004)
Journal Article
Conway, M. E., Poole, L. B., & Hutson, S. M. (2004). Roles for cysteine residues in the regulatory CXXC motif of human mitochondrial branched chain aminotransferase enzyme. Biochemistry, 43(23), 7356-7364. https://doi.org/10.1021/bi0498050

The redox-active dithiol/disulfide C315-Xaa-Xaa-C318 center has been implicated in the regulation of the human mitochondrial branched chain aminotransferase isozyme (hBCATm) [Conway, M. E., Yennawar, N., Wallin, R., Poole, L. B., and Hutson, S. M. (2... Read More about Roles for cysteine residues in the regulatory CXXC motif of human mitochondrial branched chain aminotransferase enzyme.

Effect of buffer on peak shape of peptides in reversed-phase high performance liquid chromatography (2004)
Journal Article
McCalley, D. V. (2004). Effect of buffer on peak shape of peptides in reversed-phase high performance liquid chromatography. Journal of Chromatography A, 1038(1-2), 77-84. https://doi.org/10.1016/j.chroma.2004.03.038

The effect of changing the buffer at constant low pH in the mobile phase is investigated with respect to the separation of a mixture of basic peptides. Considerably worse peak shapes, leading to poorer resolution of complex peptide mixtures, were obt... Read More about Effect of buffer on peak shape of peptides in reversed-phase high performance liquid chromatography.

Doubling the estimate of invertebrate biomass in a rainforest canopy (2004)
Journal Article
Ellwood, M. D. F., & Foster, W. A. (2004). Doubling the estimate of invertebrate biomass in a rainforest canopy. Nature, 429(6991), 549-551. https://doi.org/10.1038/nature02560

Forest canopies represent the functional interface between 90% of the Earth's terrestrial biomass and the atmosphere and include some of the most threatened of all terrestrial ecosystems. However, we lack even a basic understanding of how the biomass... Read More about Doubling the estimate of invertebrate biomass in a rainforest canopy.

Experimental implementation of mobile robot taxis with onboard Belousov-Zhabotinsky chemical medium (2004)
Journal Article
Ratcliffe, N., Adamatzky, A., Costello, B. D. L., & Melhuish, C. (2004). Experimental implementation of mobile robot taxis with onboard Belousov-Zhabotinsky chemical medium. Materials Science and Engineering: C, 24(4), 541-548. https://doi.org/10.1016/j.msec.2004.02.002

We discuss the first-ever experimental realization of the onboard excitable chemical controller for stimulus-guided navigation of mobile robots. We demonstrate that the Belousov-Zhabotinsky (BZ) reaction in the form of an onboard thin layer chemical... Read More about Experimental implementation of mobile robot taxis with onboard Belousov-Zhabotinsky chemical medium.

Voltammetric determination of 8-oxo-guanine in the presence of guanine and adenine at a screen-printed carbon electrode, and its application for the determination of oxidative DNA damage (2004)
Presentation / Conference
Honeychurch, K. C., Hart, J. P., & O'Donovan, M. (2004, May). Voltammetric determination of 8-oxo-guanine in the presence of guanine and adenine at a screen-printed carbon electrode, and its application for the determination of oxidative DNA damage. Poster presented at Biosensors 2004, Granada, Spain

Some Recent Designs and Developments of Screen-Printed Carbon Electrochemical Sensors/Biosensors for Biomedical, Environmental, and Industrial Analyses (2004)
Journal Article
Hart, J. P., Crew, A. P., Crouch, E., Honeychurch, K. C., & Pemberton, R. (2004). Some Recent Designs and Developments of Screen-Printed Carbon Electrochemical Sensors/Biosensors for Biomedical, Environmental, and Industrial Analyses. Analytical Letters, 37(5), 789-830. https://doi.org/10.1081/AL-120030682

This review describes the design and fabrication of electrochemical sensors/biosensors based on screen-printing technology and their applications in pharmaceutical, biomedical, environmental, and industrial analyses. Specific emphasis is placed on na... Read More about Some Recent Designs and Developments of Screen-Printed Carbon Electrochemical Sensors/Biosensors for Biomedical, Environmental, and Industrial Analyses.

Conditional and unconditional nonlinear stability for convection induced by absorption of radiation in a porous medium (2004)
Journal Article
Hill, A. A. (2004). Conditional and unconditional nonlinear stability for convection induced by absorption of radiation in a porous medium. Continuum Mechanics and Thermodynamics, 16(4), 305-318. https://doi.org/10.1007/s00161-003-0151-3

Convection induced by the selective absorption of radiation is investigated, for the case of an internal heat source that is modelled quadratically with respect to concentration. The growth rate for the linearised system is shown to be real, and a li... Read More about Conditional and unconditional nonlinear stability for convection induced by absorption of radiation in a porous medium.

Reaction-diffusion navigation robot control: From chemical to VLSI analogic processors (2004)
Journal Article
Rodríguez-Vázquez, A., De Lacy Costello, B., Carmona-Galán, R., Arena, P., Adamatzky, A., Basile, A., …Frasca, M. (2004). Reaction-diffusion navigation robot control: From chemical to VLSI analogic processors. IEEE Transactions on Circuits and Systems I: Regular Papers, 51(5), 926-938. https://doi.org/10.1109/TCSI.2004.827654

We introduce a new methodology and experimental implementations for real-time wave-based robot navigation in a complex, dynamically changing environment. The main idea behind the approach is to consider the robot arena as an excitable medium, in whic... Read More about Reaction-diffusion navigation robot control: From chemical to VLSI analogic processors.