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All Outputs (77)

Exploring serendipitous dialogue (2014)
Journal Article
Weitkamp, E. (2014). Exploring serendipitous dialogue. JCOM: Journal of Science Communication, 13(04),

Over the past decades there has been an increasing recognition of the need to promote dialogue between science and society. Often this takes the form of formal processes, such as citizen’s juries, that are designed to allow the public to contribut... Read More about Exploring serendipitous dialogue.

The impact of pressure and frictional heating on retention, selectivity and efficiency in ultra-high-pressure liquid chromatography (2014)
Journal Article
McCalley, D. V. (2014). The impact of pressure and frictional heating on retention, selectivity and efficiency in ultra-high-pressure liquid chromatography. Trends in Analytical Chemistry, 63, 31-43. https://doi.org/10.1016/j.trac.2014.06.024

© 2014 Elsevier B.V. The effects of pressure and frictional heating deserve serious consideration in ultra-high-pressure liquid chromatography (UHPLC) separations, as the pressures used can be three times greater than those in conventional high-perfo... Read More about The impact of pressure and frictional heating on retention, selectivity and efficiency in ultra-high-pressure liquid chromatography.

Triple negative breast cancer: The role of metabolic pathways (2014)
Journal Article
Dean, S. J., & Rhodes, A. (2014). Triple negative breast cancer: The role of metabolic pathways. Malaysian Journal of Pathology, 36(3), 155-162

The incidence of breast cancer in Malaysia and other Asian countries is on the increase, reflecting lifestyle changes some of which are known risk factors for the development of breast cancer. Most breast cancers are amenable to adjuvant therapies th... Read More about Triple negative breast cancer: The role of metabolic pathways.

Protein arginine methyltransferase 5 is a key regulator of the MYCN oncoprotein in neuroblastoma cells (2014)
Journal Article
Malik, K., Deery, M. J., Brown, K. W., Heesom, K. J., Melegh, Z., Vieira, G. C., …Malik, K. T. (2015). Protein arginine methyltransferase 5 is a key regulator of the MYCN oncoprotein in neuroblastoma cells. Molecular Oncology, 9(3), 617-627. https://doi.org/10.1016/j.molonc.2014.10.015

© 2014 The Authors. Approximately half of poor prognosis neuroblastomas (NBs) are characterized by pathognomonic MYCN gene amplification and MYCN over-expression. Here we present data showing that short-interfering RNA mediated depletion of the prote... Read More about Protein arginine methyltransferase 5 is a key regulator of the MYCN oncoprotein in neuroblastoma cells.

Serine-arginine protein kinase 1 (SRPK1) inhibition as a potential novel targeted therapeutic strategy in prostate cancer (2014)
Journal Article
Mavrou, A., Brakspear, K., Hamdollah-Zadeh, M., Damodaran, G., Babaei-Jadidi, R., Oxley, J., …Oltean, S. (2015). Serine-arginine protein kinase 1 (SRPK1) inhibition as a potential novel targeted therapeutic strategy in prostate cancer. Oncogene, 34, 4311-4319. https://doi.org/10.1038/onc.2014.360

© 2015 Macmillan Publishers Limited. All rights reserved. Angiogenesis is required for tumour growth and is induced principally by vascular endothelial growth factor A (VEGF-A). VEGF-A pre-mRNA is alternatively spliced at the terminal exon to produce... Read More about Serine-arginine protein kinase 1 (SRPK1) inhibition as a potential novel targeted therapeutic strategy in prostate cancer.

Assessing the value of imperfect biocontainment nationally: Rapeseed in the United Kingdom as an exemplar (2014)
Journal Article
Ford, C. S., Allainguillaume, J., Fu, T. R., Mitchley, J., & Wilkinson, M. J. (2015). Assessing the value of imperfect biocontainment nationally: Rapeseed in the United Kingdom as an exemplar. New Phytologist, 205(3), 1342-1349. https://doi.org/10.1111/nph.13131

© 2014 New Phytologist Trust. Paternal biocontainment methods (PBMs) act by preventing pollen-mediated transgene flow. They are compromised by transgene escape via the crop-maternal line. We therefore assess the efficacy of PBMs for transgenic rapese... Read More about Assessing the value of imperfect biocontainment nationally: Rapeseed in the United Kingdom as an exemplar.

City life makes females fussy: Sex differences in habitat use of temperate bats in urban areas (2014)
Journal Article
Park, K. J., Mayhew, R. J., Lintott, P., Bunnefeld, N., Fuentes-Montemayor, E., Minderman, J., & Olley, L. (2014). City life makes females fussy: Sex differences in habitat use of temperate bats in urban areas. Royal Society Open Science, 1(3), Article 140200. https://doi.org/10.1098/rsos.140200

© 2014 The Authors. Urbanization is a major driver of the global loss of biodiversity; to mitigate its adverse effects, it is essential to understand what drives species' patterns of habitat use within the urban matrix. While many animal species are... Read More about City life makes females fussy: Sex differences in habitat use of temperate bats in urban areas.

Topographical variation reduces phenological mismatch between a butterfly and its nectar source (2014)
Journal Article
Hindle, B. J., Kerr, C. L., Richards, S. A., & Willis, S. G. (2015). Topographical variation reduces phenological mismatch between a butterfly and its nectar source. Journal of Insect Conservation, 19(2), 227-236. https://doi.org/10.1007/s10841-014-9713-x

© 2014, Springer International Publishing Switzerland. The timing of many biological events, including butterfly imago emergence, has advanced under climate change, with the rate of these phenological changes often differing among taxonomic groups. S... Read More about Topographical variation reduces phenological mismatch between a butterfly and its nectar source.

Direct mixing of atomistic solutes and coarse-grained water (2014)
Journal Article
Orsi, M., Ding, W., & Palaiokostas, M. (2014). Direct mixing of atomistic solutes and coarse-grained water. Journal of Chemical Theory and Computation, 10(10), 4684-4693. https://doi.org/10.1021/ct500065k

© 2014 American Chemical Society. We present a new dual-resolution approach for coupling atomistic and coarse-grained models in molecular dynamics simulations of hydrated systems. In particular, a coarse-grained point dipolar water model is used to s... Read More about Direct mixing of atomistic solutes and coarse-grained water.

Convective stability of carbon sequestration in anisotropic porous media (2014)
Journal Article
Hill, A. A., & Morad, M. R. (2014). Convective stability of carbon sequestration in anisotropic porous media. Proceedings of the Royal Society A: Mathematical, Physical and Engineering Sciences, 470(2170), https://doi.org/10.1098/rspa.2014.0373

© 2014 The Author(s) Published by the Royal Society. All rights reserved. The stability of convection in an anisotropic porous medium, where the solute concentration is assumed to decay via a first-order chemical reaction, is studied. This is a simpl... Read More about Convective stability of carbon sequestration in anisotropic porous media.

Atmin is a transcriptional regulator of both lung morphogenesis and ciliogenesis (2014)
Journal Article
Stevens, J. L., Goggolidou, P., L. Stevens, J., Agueci, F., Keynton, J., Wheway, G., …Norris, D. P. (2014). Atmin is a transcriptional regulator of both lung morphogenesis and ciliogenesis. Development, 141(20), 3966-3977. https://doi.org/10.1242/dev.107755

© 2014. Initially identified in DNA damage repair, ATM-interactor (ATMIN) further functions as a transcriptional regulator of lung morphogenesis. Here we analyse three mouse mutants, Atmingpg6/gpg6, AtminH210Q/H210Q and Dynll1GT/GT, revealing how ATM... Read More about Atmin is a transcriptional regulator of both lung morphogenesis and ciliogenesis.

Novel reductive-reductive mode electrochemical detection of Rohypnol following liquid chromatography and its determination in coffee (2014)
Journal Article
Honeychurch, K. C., Davidson, G. M., Brown, E., & Hart, J. P. (2015). Novel reductive-reductive mode electrochemical detection of Rohypnol following liquid chromatography and its determination in coffee. Analytica Chimica Acta, 853, 222-227. https://doi.org/10.1016/j.aca.2014.09.033

© 2014 Elsevier B.V. Rohypnol (flunitrazepam) has been successfully determined in coffee by high performance liquid chromatography dual electrode detection (LC-DED) in the dual reductive mode. Initial studies were performed to optimise the chromatogr... Read More about Novel reductive-reductive mode electrochemical detection of Rohypnol following liquid chromatography and its determination in coffee.

On the roles of scientists, press officers and journalists (2014)
Journal Article
Weitkamp, E. (2014). On the roles of scientists, press officers and journalists. JCOM: Journal of Science Communication, 13(03),

This issue of the Journal of Science Communication raises a number of questions about the ways that new scientific research emerges from research institutions and in particular the role played by scientists, press officers and journalists in this... Read More about On the roles of scientists, press officers and journalists.

Rahnella victoriana sp. nov., Rahnella bruchi sp. nov., Rahnella woolbedingensis sp. nov., classification of Rahnella genomospecies 2 and 3 as Rahnella variigena sp. nov. and Rahnella inusitata sp. nov., respectively and emended description of the genus Rahnella (2014)
Journal Article
Brady, C., Hunter, G., Kirk, S., Arnold, D. L., & Denman, S. (2014). Rahnella victoriana sp. nov., Rahnella bruchi sp. nov., Rahnella woolbedingensis sp. nov., classification of Rahnella genomospecies 2 and 3 as Rahnella variigena sp. nov. and Rahnella inusitata sp. nov., respectively and emended description of the genus Rahnella. Systematic and Applied Microbiology, 37(8), 545-552. https://doi.org/10.1016/j.syapm.2014.09.001

© 2014 Published by Elsevier GmbH. Isolations from oak symptomatic of Acute Oak Decline, alder and walnut log tissue, and buprestid beetles in 2009-2012 yielded 32 Gram-negative bacterial strains showing highest gyrB sequence similarity to Rahnella a... Read More about Rahnella victoriana sp. nov., Rahnella bruchi sp. nov., Rahnella woolbedingensis sp. nov., classification of Rahnella genomospecies 2 and 3 as Rahnella variigena sp. nov. and Rahnella inusitata sp. nov., respectively and emended description of the genus Rahnella.

Congenital Malaria Among Inborn And Out Born Babies At A Tertiary Care Hospital In Port Harcourt, Rivers State, South- South Nigeria (2014)
Journal Article
Akpiri, R. U. (2014). Congenital Malaria Among Inborn And Out Born Babies At A Tertiary Care Hospital In Port Harcourt, Rivers State, South- South Nigeria. Journal of Natural Sciences Research, 4(5),

Congenital malaria is increasingly reported among babies born to mothers residing in endemic areas. Congenital malaria is a major problem in tropical and subtropical countries, it can be transferred vertically from the placenta of an infected pregnan... Read More about Congenital Malaria Among Inborn And Out Born Babies At A Tertiary Care Hospital In Port Harcourt, Rivers State, South- South Nigeria.

Development of a disposable screen-printed amperometric biosensor based on glutamate dehydrogenase, for the determination of glutamate in clinical and food applications (2014)
Journal Article
Hughes, G., Pemberton, R., Fielden, P., & Hart, J. P. (2014). Development of a disposable screen-printed amperometric biosensor based on glutamate dehydrogenase, for the determination of glutamate in clinical and food applications. Analytical & Bioanalytical Electrochemistry, 6(4), 435-449

A screen printed carbon electrode (SPCE) containing the electrocatalyst Meldola’s Blue (MB) has been investigated as the base transducer for a glutamate biosensor. The sandwich biosensor was fabricated by firstly depositing a chitosan (CHIT) layer... Read More about Development of a disposable screen-printed amperometric biosensor based on glutamate dehydrogenase, for the determination of glutamate in clinical and food applications.

Alternative splicing of TIA-1 in human colon cancer regulates VEGF isoform expression, angiogenesis, tumour growth and bevacizumab resistance (2014)
Journal Article
Hamdollah Zadeh, M. A., Amin, E. M., Hoareau-Aveilla, C., Domingo, E., Symonds, K. E., Ye, X., …Bates, D. O. (2015). Alternative splicing of TIA-1 in human colon cancer regulates VEGF isoform expression, angiogenesis, tumour growth and bevacizumab resistance. Molecular Oncology, 9(1), 167-178. https://doi.org/10.1016/j.molonc.2014.07.017

© 2014 The Authors. The angiogenic capability of colorectal carcinomas (CRC), and their susceptibility to anti-angiogenic therapy, is determined by expression of vascular endothelial growth factor (VEGF) isoforms. The intracellular protein T-cell In... Read More about Alternative splicing of TIA-1 in human colon cancer regulates VEGF isoform expression, angiogenesis, tumour growth and bevacizumab resistance.

Development of a hydrogen peroxide sensor based on screen-printed electrodes modified with inkjet-printed prussian blue nanoparticles (2014)
Journal Article
Cinti, S., Arduini, F., Moscone, D., Palleschi, G., & Killard, A. (2014). Development of a hydrogen peroxide sensor based on screen-printed electrodes modified with inkjet-printed prussian blue nanoparticles. Sensors, 14(8), 14222-14234. https://doi.org/10.3390/s140814222

A sensor for the simple and sensitive measurement of hydrogen peroxide has been developed which is based on screen printed electrodes (SPEs) modified with Prussian blue nanoparticles (PBNPs) deposited using piezoelectric inkjet printing. PBNP-modifie... Read More about Development of a hydrogen peroxide sensor based on screen-printed electrodes modified with inkjet-printed prussian blue nanoparticles.

Using Participatory Risk Mapping (PRM) to identify and understand people's perceptions of crop loss to animals in uganda (2014)
Journal Article
Webber, A. D., & Hill, C. M. (2014). Using Participatory Risk Mapping (PRM) to identify and understand people's perceptions of crop loss to animals in uganda. PLoS ONE, 9(7), e102912. https://doi.org/10.1371/journal.pone.0102912

Considering how people perceive risks to their livelihoods from local wildlife is central to (i) understanding the impact of crop damage by animals on local people and (ii) recognising how this influences their interactions with, and attitudes toward... Read More about Using Participatory Risk Mapping (PRM) to identify and understand people's perceptions of crop loss to animals in uganda.