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All Outputs (26)

The economics of the primate trade in Bioko, Equatorial Guinea (2005)
Journal Article
Reid, J., Morra, W., Posa Bohome, C., & Fernández Sobrado, D. (2005). The economics of the primate trade in Bioko, Equatorial Guinea

Researchers from the National University of Equatorial Guinea (UNGE) and Arcadia University have alerted the international conservation community to the threat of imminent extinction of the seven primate sub-species on the island of Bioko, Equatorial... Read More about The economics of the primate trade in Bioko, Equatorial Guinea.

The framing of nanotechnologies in the British newspaper press (2005)
Journal Article
Anderson, A., Allan, S., Petersen, A., & Wilkinson, C. (2005). The framing of nanotechnologies in the British newspaper press. Science Communication, 27(2), 200-220. https://doi.org/10.1177/1075547005281472

This article investigates how developments in nanotechnology were framed in the British national newspaper press during a formative period in their rising public salience. Specifically, an intervention by Prince Charles in April 2003 is shown to have... Read More about The framing of nanotechnologies in the British newspaper press.

Wear of dentine in vitro by toothpaste abrasives and detergents alone and combined (2005)
Journal Article
Moore, C., & Addy, M. (2005). Wear of dentine in vitro by toothpaste abrasives and detergents alone and combined. Journal of Clinical Periodontology, 32(12), 1242-1246. https://doi.org/10.1111/j.1600-051x.2005.00857.x

Aim: To measure in vitro the abrasion of dentine by toothpaste detergents and abrasives alone and combined. Materials and Methods: Detergents used were tego betain, sodium lauryl sulphate (SLS), adinol and pluronic diluted to 1%w/v. Abrasives were th... Read More about Wear of dentine in vitro by toothpaste abrasives and detergents alone and combined.

Structural determinants for branched-chain aminotransferase isozyme-specific inhibition by the anticonvulsant drug gabapentin (2005)
Journal Article
Yennawar, N., Goto, M., Miyahara, I., Hirotsu, K., Conway, M., Islam, M. M., & Hutson, S. M. (2005). Structural determinants for branched-chain aminotransferase isozyme-specific inhibition by the anticonvulsant drug gabapentin. Journal of Biological Chemistry, 280(44), 37246-37256. https://doi.org/10.1074/jbc.M506486200

This study presents the first three-dimensional structures of human cytosolic branched-chain aminotransferase (hBCATc) isozyme complexed with the neuroactive drug gabapentin, the hBCATc Michaelis complex with the substrate analog, 4-methylvalerate, a... Read More about Structural determinants for branched-chain aminotransferase isozyme-specific inhibition by the anticonvulsant drug gabapentin.

Bone marrow-derived mesenchymal stem cells (2005)
Journal Article
Hows, J., Kemp, K. C., & Donaldson, C. (2005). Bone marrow-derived mesenchymal stem cells. Leukemia & Lymphoma, 46(11), 1531-1544. https://doi.org/10.1080/10428190500215076

Human mesenchymal stem cells (MSCs) contribute to the regeneration of mesenchymal tissues, and are essential in providing support for the growth and differentiation of primitive hemopoietic cells within the bone marrow micro-environment. Techniques a... Read More about Bone marrow-derived mesenchymal stem cells.

Global hypomethylation of the genome in XX embryonic stem cells (2005)
Journal Article
Zvetkova, I., Apedaile, A., Ramsahoye, B., Mermoud, J. E., Crompton, L., John, R., …Brockdorff, N. (2005). Global hypomethylation of the genome in XX embryonic stem cells. Nature Genetics, 37(11), 1274-1279. https://doi.org/10.1038/ng1663

Embryonic stem (ES) cells are important tools in the study of gene function and may also become important in cell therapy applications. Establishment of stable XX ES cell lines from mouse blastocysts is relatively problematic owing to frequent loss o... Read More about Global hypomethylation of the genome in XX embryonic stem cells.

Cloning and mapping of the porcine cytochrome-p450 2E1 gene and its association with skatole levels in the domestic pig (2005)
Journal Article
McGivan, J. D., Skinner, T. M., Doran (nee Udovikova), O., Haley, C. S., & Archibald, A. L. (2005). Cloning and mapping of the porcine cytochrome-p450 2E1 gene and its association with skatole levels in the domestic pig. Animal Genetics, 36(5), 417-422. https://doi.org/10.1111/j.1365-2052.2005.01342.x

The porcine cytochrome-p450 2E1 (CYP2E1) gene was isolated by screening a pig BAC library and partially sequenced. This sequence information was used to identify six single nucleotide polymorphisms (SNPs) within the CYP2E1 gene and its promoter. In a... Read More about Cloning and mapping of the porcine cytochrome-p450 2E1 gene and its association with skatole levels in the domestic pig.

Species selection for phytoremediation of 36Cl/35Cl using angiosperm phylogeny and inter-taxa differences in uptake (2005)
Journal Article
Willey, N., & Fawcett, K. (2005). Species selection for phytoremediation of 36Cl/35Cl using angiosperm phylogeny and inter-taxa differences in uptake. International Journal of Phytoremediation, 7(4), 295-306. https://doi.org/10.1080/16226510500327152

High concentrations of 35Cl and the radioisotope 36Cl (produced naturally by cosmic radiation and anthropogenically by U fission and the use of neutron sources) can be problematic in soil, but are potentially amenable to phytoremediation if appropria... Read More about Species selection for phytoremediation of 36Cl/35Cl using angiosperm phylogeny and inter-taxa differences in uptake.

Proteomic identification of glyceraldehyde 3-phosphate dehydrogenase as an inhibitory target of hydrogen peroxide in Arabidopsis (2005)
Journal Article
Harrison, J., Hancock, J. T., Henson, D., Nyirenda, M., Desikan, R., Lewis, M., …Neill, S. (2005). Proteomic identification of glyceraldehyde 3-phosphate dehydrogenase as an inhibitory target of hydrogen peroxide in Arabidopsis. Plant Physiology and Biochemistry, 43(9), 828-835. https://doi.org/10.1016/j.plaphy.2005.07.012

Hydrogen peroxide (H2O2) is now recognised as a key signalling molecule in eukaryotes. In plants, H2O2 is involved in regulating stomatal closure, gravitropic responses, gene expression and programmed cell death. Although several kinases, such as oxi... Read More about Proteomic identification of glyceraldehyde 3-phosphate dehydrogenase as an inhibitory target of hydrogen peroxide in Arabidopsis.

Predicting inter-taxa differences in plant uptake of cesium-134/137 (2005)
Journal Article
Willey, N., Tang, S., & Watt, N. R. (2005). Predicting inter-taxa differences in plant uptake of cesium-134/137. Journal of Environmental Quality, 34(5), 1478-1489. https://doi.org/10.2134/jeq2004.0454

For 134/137Cs, and many other soil contaminants, research into transfer to plants has focused on particular crops and phytoremediation candidates, producing uptake data for a small proportion of all plant taxa. Despite the significance of differences... Read More about Predicting inter-taxa differences in plant uptake of cesium-134/137.

The endogenous cannabinoid, anandamide, induces cell death in colorectal carcinoma cells: A possible role for cyclooxygenase 2 (2005)
Journal Article
Patsos, H. A., Hicks, D. J., Dobson, R. R., Greenhough, A., Woodman, N., Lane, J. D., …Paraskeva, C. (2005). The endogenous cannabinoid, anandamide, induces cell death in colorectal carcinoma cells: A possible role for cyclooxygenase 2. Gut, 54(12), 1741-1750. https://doi.org/10.1136/gut.2005.073403

Background and aims: Cyclooxygenase 2 (COX-2) is upregulated in most colorectal cancers and is responsible for metabolism of the endogenous cannabinoid, anandamide, into prostaglandin-ethanolamides (PG-EAs). The aims of this study were to determine w... Read More about The endogenous cannabinoid, anandamide, induces cell death in colorectal carcinoma cells: A possible role for cyclooxygenase 2.

Experimental implementation of collision-based gates in Belousov-Zhabotinsky medium (2005)
Journal Article
de Lacy Costello, B., & Adamatzky, A. (2005). Experimental implementation of collision-based gates in Belousov-Zhabotinsky medium. Chaos, Solitons and Fractals, 25(3), 535-544. https://doi.org/10.1016/j.chaos.2004.11.056

We experimentally demonstrate that excitation wave-fragments in a Belousov-Zhabotinsky (BZ) medium with immobilised catalyst can be used to build elementary logical gates and circuits. Following our previous theoretical constructions [Adamatzky A. Co... Read More about Experimental implementation of collision-based gates in Belousov-Zhabotinsky medium.

Cannabinoids and cancer: Potential for colorectal cancer therapy (2005)
Journal Article
Patsos, H. A., Hicks, D. J., Greenhough, A., Williams, A. C., & Paraskeva, C. (2005). Cannabinoids and cancer: Potential for colorectal cancer therapy. Biochemical Society Transactions, 33(4), 712-714. https://doi.org/10.1042/BST0330712

Despite extensive research into the biology of CRC (colorectal cancer), and recent advances in surgical techniques and chemotherapy, CRC continues to be a major cause of death throughout the world. Therefore it is important to develop novel chemoprev... Read More about Cannabinoids and cancer: Potential for colorectal cancer therapy.

Cruciate ligament laxity and femoral intercondylar notch narrowing in early-stage knee osteoarthritis (2005)
Journal Article
Quasnichka, H. L., Anderson-MacKenzie, J. M., Tarlton, J. F., Sims, T. J., Billingham, M. E. J., & Bailey, A. J. (2005). Cruciate ligament laxity and femoral intercondylar notch narrowing in early-stage knee osteoarthritis. Arthritis and Rheumatism, 52(10), 3100-3109. https://doi.org/10.1002/art.21340

Objective. The influence of the cruciate ligaments in spontaneous osteoarthritis (OA) is not understood, although ligament rupture is known to cause secondary OA. Additionally, femoral notch narrowing at the anterior cruciate ligament (ACL) insertion... Read More about Cruciate ligament laxity and femoral intercondylar notch narrowing in early-stage knee osteoarthritis.

Study of overloading of basic drugs and peptides in reversed-phase high-performance liquid chromatography using pH adjustment of weak acid mobile phases suitable for mass spectrometry (2005)
Journal Article
McCalley, D. V. (2005). Study of overloading of basic drugs and peptides in reversed-phase high-performance liquid chromatography using pH adjustment of weak acid mobile phases suitable for mass spectrometry. Journal of Chromatography A, 1075(1-2), 57-64. https://doi.org/10.1016/j.chroma.2005.02.090

Serious losses in column efficiency for ionised basic drugs and peptides occur due to overloading of C18 phases when weak acid mobile phases of low ionic strength suitable for mass spectrometric detection are used. Measurable changes in retention tim... Read More about Study of overloading of basic drugs and peptides in reversed-phase high-performance liquid chromatography using pH adjustment of weak acid mobile phases suitable for mass spectrometry.

Voltammetric determination of urinary 1-hydroxypyrene using molecularly imprinted polymer-modified screen-printed carbon electrodes (2005)
Journal Article
Kirsch, N., Honeychurch, K. C., Hart, J. P., & Whitcombe, M. J. (2005). Voltammetric determination of urinary 1-hydroxypyrene using molecularly imprinted polymer-modified screen-printed carbon electrodes. Electroanalysis, 17(7), 571-578. https://doi.org/10.1002/elan.200403131

A two step non-competitive affinity method for the trace determination of 1-hydroxypyrene (1-OHP) using a disposable molecularly imprinted polymer (MIP) modified screen-printed carbon electrode (MIP-SPCE) has been developed. The MIP was synthesized a... Read More about Voltammetric determination of urinary 1-hydroxypyrene using molecularly imprinted polymer-modified screen-printed carbon electrodes.

Double-diffusive convection in a porous medium with a concentration based internal heat source (2005)
Journal Article
Hill, A. A. (2005). Double-diffusive convection in a porous medium with a concentration based internal heat source. Proceedings of the Royal Society A: Mathematical, Physical and Engineering Sciences, 461(2054), 561-574. https://doi.org/10.1098/rspa.2004.1328

Linear and nonlinear stability analyses of double-diffusive convection in a fluid-saturated porous layer with a concentration based internal heat source are studied. Darcy's law and the Boussinesq approximation are employed, with the equation of stat... Read More about Double-diffusive convection in a porous medium with a concentration based internal heat source.