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Resistance to echinocandin antifungal agents in the United Kingdom in clinical isolates of Candida glabrata: Fifteen years of interpretation and assessment (2019)
Journal Article
Fraser, M., Borman, A. M., Thorn, R., & Lawrance, L. M. (2020). Resistance to echinocandin antifungal agents in the United Kingdom in clinical isolates of Candida glabrata: Fifteen years of interpretation and assessment. Medical Mycology, 58(2), 219-226. https://doi.org/10.1093/mmy/myz053

Candidaemia is widely reported as the fourth most common form of bloodstream infection worldwide. Reports of breakthrough cases of candidaemia are increasing, especially in the context of a move away from azole antifungals as prophylactic or first li... Read More about Resistance to echinocandin antifungal agents in the United Kingdom in clinical isolates of Candida glabrata: Fifteen years of interpretation and assessment.

Multi-locus sequence typing of Escherichia coli isolates with acquired ampC genes and ampC promoter mutations (2016)
Journal Article
Lawrance, L. M., Moore, P. C., Lewis, J. A., Moore, P. C. L., Arnold, D. L., & Lawrance, L. (2016). Multi-locus sequence typing of Escherichia coli isolates with acquired ampC genes and ampC promoter mutations. Diagnostic Microbiology and Infectious Disease, 86(3), 265-267. https://doi.org/10.1016/j.diagmicrobio.2016.08.008

© 2016 Elsevier Inc. Multi-locus sequence typing was used to reveal a high degree of diversity amongst the E. coli isolates with AmpC plasmid genes, and a high prevalence of the −32 mutation present.

Chromosomal ampC mutations in cefpodoxime-resistant, ESBL-negative uropathogenic Escherichia coli (2015)
Journal Article
Lawrance, L. M., Arnold, D. L., Moore, P. C., Lewis, J. A., Moore, P. M., Arnold, D. L., & Lawrance, L. (2015). Chromosomal ampC mutations in cefpodoxime-resistant, ESBL-negative uropathogenic Escherichia coli. British Journal of Biomedical Science, 72(1), 7-11. https://doi.org/10.1080/09674845.2015.11666789

AmpC β-lactamase is an enzyme commonly produced by Escherichia coli that causes resistance to cephalosporins and penicillins. Enzyme production is controlled by the strength of the promoter encoded by the chromosomal ampC gene, with the level of prod... Read More about Chromosomal ampC mutations in cefpodoxime-resistant, ESBL-negative uropathogenic Escherichia coli.