All Outputs (3)

The implementation, impact and effectiveness of surveillance systems on the prevention and transmission of carbapenemase-producing organisms (2021)
Thesis
Henderson, J. The implementation, impact and effectiveness of surveillance systems on the prevention and transmission of carbapenemase-producing organisms. (Thesis). University of the West of England. Retrieved from https://uwe-repository.worktribe.com/output/6093082

Carbapenems are broad spectrum antibiotics often reserved for the critically ill. Their increased and, often, inappropriate use, has led to the development of resistance, through acquisition of carbapenemase enzymes. There are five carbapenemases tha... Read More about The implementation, impact and effectiveness of surveillance systems on the prevention and transmission of carbapenemase-producing organisms.

A point prevalence study to determine the inpatient rate of carbapenemase-producing organisms at a large London NHS Trust (2019)
Journal Article
Henderson, J., Ciesielczuk, H., Nelson, S., Wilks, M., & Cummins, M. (2020). A point prevalence study to determine the inpatient rate of carbapenemase-producing organisms at a large London NHS Trust. Journal of Hospital Infection, 104(1), 12-19. https://doi.org/10.1016/j.jhin.2019.10.012

Summary Background There has been an increase in the number of carbapenemase-producing organisms documented across the UK over the past 10 years. From these, the ‘big five’ carbapenemases (KPC, OXA-48, IMP, VIM, and NDM) are the most common types r... Read More about A point prevalence study to determine the inpatient rate of carbapenemase-producing organisms at a large London NHS Trust.

Prevalence of Carbapenemase Producing Organisms in East London, UK
Presentation / Conference
Henderson, J., Ciesielczuk, H., & Nelson, S. Prevalence of Carbapenemase Producing Organisms in East London, UK. Poster presented at American Society for Microbiology, Microbe 2019, San Francisco, USA

Carbapenemases are enzymes, produced by an array of common Gram-negative organisms, which hydrolyse the carbapenem antibiotics, conferring resistance. The main protagonists are the “big five” carbapenemases, KPC, OXA-48, IMP, VIM and NDM, which have... Read More about Prevalence of Carbapenemase Producing Organisms in East London, UK.