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A point prevalence study to determine the inpatient rate of carbapenemase-producing organisms at a large London NHS Trust (2019)
Journal Article
Henderson, J., Ciesielczuk, H., Nelson, S., Wilks, M., & Cummins, M. (2020). A point prevalence study to determine the inpatient rate of carbapenemase-producing organisms at a large London NHS Trust. Journal of Hospital Infection, 104(1), 12-19. https://doi.org/10.1016/j.jhin.2019.10.012

Summary Background There has been an increase in the number of carbapenemase-producing organisms documented across the UK over the past 10 years. From these, the ‘big five’ carbapenemases (KPC, OXA-48, IMP, VIM, and NDM) are the most common types r... Read More about A point prevalence study to determine the inpatient rate of carbapenemase-producing organisms at a large London NHS Trust.

Community prevalence of carbapenemase-producing organisms in East London (2019)
Journal Article
Henderson, J., Ciesielczuk, H., Nelson, S. M., & Wilks, M. (2019). Community prevalence of carbapenemase-producing organisms in East London. Journal of Hospital Infection, 103(2), 142-146. https://doi.org/10.1016/j.jhin.2019.04.014

Background: Over the last decade there has been a rapid, worldwide increase in carbapenem resistance, which is of growing concern. The main protagonists, the carbapenemases Klebsiella pneumoniae carbapenemase (KPC), oxacillinase β-lactamase 48 (OXA-4... Read More about Community prevalence of carbapenemase-producing organisms in East London.

An in vitro biofilm model of Staphylococcus aureus infection of bone (2019)
Journal Article
Sweeney, E., Lovering, A., Bowker, K., MacGowan, A., & Nelson, S. (2019). An in vitro biofilm model of Staphylococcus aureus infection of bone. Letters in Applied Microbiology, 68(4), 294-302. https://doi.org/10.1111/lam.13131

Chronic osteomyelitis is difficult to treat, with biofilm growth and the diffusion barrier to antibiotics presented by bone contributory factors. The aim of this study was to develop and evaluate an invitro model of osteomyelitis. A bioluminescent st... Read More about An in vitro biofilm model of Staphylococcus aureus infection of bone.

Pharmacodynamics of ciprofloxacin against Pseudomonas aeruginosa planktonic and biofilm‐derived cells (2019)
Journal Article
Marques, C., & Nelson, S. (2019). Pharmacodynamics of ciprofloxacin against Pseudomonas aeruginosa planktonic and biofilm‐derived cells. Letters in Applied Microbiology, 68(4), 350-359. https://doi.org/10.1111/lam.13126

© 2019 The Society for Applied Microbiology The influence of growth phase and state on the survival and recovery of Pseudomonas aeruginosa exposed to ciprofloxacin was investigated using batch culture grown planktonic cells and disaggregated biofilm... Read More about Pharmacodynamics of ciprofloxacin against Pseudomonas aeruginosa planktonic and biofilm‐derived cells.

Characterization of the Salmonella bacteriophage vB_SenS-Ent1 (2012)
Journal Article
Reynolds, D., Nelson, S., Turner, D., Hezwani, M., Nelson, S., Salisbury, V., & Reynolds, D. M. (2012). Characterization of the Salmonella bacteriophage vB_SenS-Ent1. Journal of General Virology, 93(PART 9), 2046-2056. https://doi.org/10.1099/vir.0.043331-0

The bacteriophage vB_SenS-Ent1 (Ent1) is a member of the family Siphoviridae of tailed bacteriophages and infects a broad range of serovars of the enteric pathogen Salmonella enterica. The virion particle is composed of an icosahedral head 64 nm in d... Read More about Characterization of the Salmonella bacteriophage vB_SenS-Ent1.

Characterization of the Salmonella bacteriophage vB_SenS-Ent1 (2012)
Journal Article
Turner, D., Hezwani, M., Nelson, S., Salisbury, V., & Reynolds, D. M. (2012). Characterization of the Salmonella bacteriophage vB_SenS-Ent1. Journal of General Virology, 93(9), 2046-2056. https://doi.org/10.1099/vir.0.043331-0

The bacteriophage vB_SenS-Ent1 (Ent1) is a member of the family Siphoviridae of tailed bacteriophages and infects a broad range of serovars of the enteric pathogen Salmonella enterica. The virion particle is composed of an icosahedral head 64 nm in d... Read More about Characterization of the Salmonella bacteriophage vB_SenS-Ent1.

Use of a bioluminescent Pseudomonas aeruginosa strain within an in vitro microbiological system, as a model of wound infection, to assess the antimicrobial efficacy of wound dressings by monitoring light production (2007)
Journal Article
Greenman, J., Nelson, S. M., Thorn, R. M., Thorn, R., Nelson, S., & Greenman, J. (2007). Use of a bioluminescent Pseudomonas aeruginosa strain within an in vitro microbiological system, as a model of wound infection, to assess the antimicrobial efficacy of wound dressings by monitoring light production. Antimicrobial Agents and Chemotherapy, 51(9), 3217-3224. https://doi.org/10.1128/AAC.00302-07

A bioluminescent Pseudomonas aeruginosa was incorporated into an in vitro static diffusion method to determine whether light output could be used as a measure of wound dressing efficacy. A significant linear correlation was observed between viable co... Read More about Use of a bioluminescent Pseudomonas aeruginosa strain within an in vitro microbiological system, as a model of wound infection, to assess the antimicrobial efficacy of wound dressings by monitoring light production.

Use of bioluminescent Escherichia coli O157:H7 to study intra-protozoan survival of bacteria within Tetrahymena pyriformis (2003)
Journal Article
Salisbury, V. C., Taylor, E. L., Cooper, A. A., Nelson, S. M., Nelson, S., Cooper, A., …Salisbury, V. (2003). Use of bioluminescent Escherichia coli O157:H7 to study intra-protozoan survival of bacteria within Tetrahymena pyriformis. FEMS Microbiology Letters, 223(1), 95-99. https://doi.org/10.1016/S0378-1097%2803%2900349-5

A method was developed that enabled real-time monitoring of the uptake and survival of bioluminescent Escherichia coli O157 within the freshwater ciliate Tetrahymena pyriformis. Constitutively bioluminescent E. coli O157 pLITE27 was cocultured with T... Read More about Use of bioluminescent Escherichia coli O157:H7 to study intra-protozoan survival of bacteria within Tetrahymena pyriformis.