All Outputs (11)

Determination of licit and illicit drugs and metabolites in human sweat by liquid chromatography-tandem mass spectrometry (2023)
Journal Article

A liquid chromatography-tandem mass spectrometry screening method in sweat was developed for the simultaneous determination of three licit drugs (nicotine, paracetamol, and caffeine); four illicit drugs (cocaine, ketamine, 25I-NBOMe and methamphetami... Read More about Determination of licit and illicit drugs and metabolites in human sweat by liquid chromatography-tandem mass spectrometry.

Illicit drug contamination of the Bristol Pound local currency (2020)
Journal Article

Reports have shown the prevalence of the contamination of banknotes with a number of different drugs. These studies have focused on investigating drug contamination levels on currency which is either nationally or even international distributed. To p... Read More about Illicit drug contamination of the Bristol Pound local currency.

Extraction-free, direct determination of caffeine in microliter volumes of beverages by thermal desorption-gas chromatography mass spectrometry (2020)
Journal Article

An extraction-free method requiring microliter (μL) volumes has been developed for the determination of caffeine in beverages.
Using a pyrolysis-gas chromatography mass spectrometry system, the conditions required for the direct thermal desorption-g... Read More about Extraction-free, direct determination of caffeine in microliter volumes of beverages by thermal desorption-gas chromatography mass spectrometry.

Novel blood biomarkers that correlate with cognitive performance and hippocampal volumetry: Potential for early diagnosis of Alzheimer's disease (2019)
Journal Article

© 2019 - IOS Press and the authors. All rights reserved. Background: Differential diagnosis of people presenting with mild cognitive impairment (MCI) that will progress to Alzheimer's disease (AD) remains clinically challenging. Current criteria used... Read More about Novel blood biomarkers that correlate with cognitive performance and hippocampal volumetry: Potential for early diagnosis of Alzheimer's disease.

Direct thermal desorption gas chromatographic determination of ethylene glycol in whole blood (2018)
Presentation / Conference Contribution

Outline of talk

Ethylene glycol
Problems of analysis
Our new approach
Optimisation studies
Analytical performance characteristics
Analytical application
Areas of future work
Conclusions
Acknowledgements

Direct thermal desorption gas chromatographic determination of toxicological relevant concentrations of ethylene glycol in whole blood (2018)
Presentation / Conference Contribution

Ethylene Glycol has been determined directly in whole blood using thermal desorption gas chromatography. Recoveries of between 84.8 % to 107 % were recorded, with corresponding %CV of between 1.7 % and 5.8 %. No extraction or derivatization steps w... Read More about Direct thermal desorption gas chromatographic determination of toxicological relevant concentrations of ethylene glycol in whole blood.

Direct thermal desorption gas chromatographic determination of toxicologically relevant concentrations of ethylene glycol in whole blood (2018)
Journal Article

© 2018 The Royal Society of Chemistry. A simple and rapid method involving thermal desorption gas chromatography (TD-GC) with flame ionisation detection has been successfully developed for the determination of ethylene glycol in whole blood. No sampl... Read More about Direct thermal desorption gas chromatographic determination of toxicologically relevant concentrations of ethylene glycol in whole blood.

Determination of caffeine and paracetamol in Bristol harbour water by LC/MS/MS (2017)
Presentation / Conference Contribution

Anthropogenic inputs such as caffeine and paracetamol can be used as possible chemical markers of sewage pollution as their presence can be presumed to result from human sewage inputs.
In this present investigation we determined the concentrations... Read More about Determination of caffeine and paracetamol in Bristol harbour water by LC/MS/MS.

Coupled electrochemical mass spectrometry investigations of the oxidation of nicotine and its determination in third-hand smoke by liquid chromatography electrochemical detection (2017)
Presentation / Conference Contribution

The electrochemistry of nicotine
Electrochemical mass spectrometry of nicotine
What is third-hand smoke?
Why is it important environmentally?
Liquid chromatography electrochemical detection of third-hand smoke
Conclusions

Liquid Chromatography Electrochemical Determination of Nicotine in Third-Hand Smoke (2016)
Journal Article

© 2017 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim Third-hand smoke (THS) can be defined as the contamination of surfaces by second-hand smoke. This residue can form further pollutants which can be re-suspended in dust or be re-emitted into the gas... Read More about Liquid Chromatography Electrochemical Determination of Nicotine in Third-Hand Smoke.

A simple and rapid method for the determination of nicotine in third-hand smoke by liquid chromatography and its application for the assessment of contaminated outdoor communal areas (2016)
Journal Article

Copyright © 2015 John Wiley & Sons, Ltd. This is the first report on the determination of nicotine in third-hand smoke (THS) in outdoor communal areas. The term THS can be defined as the contamination of surfaces by second-hand smoke. This can rema... Read More about A simple and rapid method for the determination of nicotine in third-hand smoke by liquid chromatography and its application for the assessment of contaminated outdoor communal areas.