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Electrical properties of proteinoids for unconventional computing architectures (2023)
Conference Proceeding
Mougkogiannis, P., & Adamatzky, A. (2023). Electrical properties of proteinoids for unconventional computing architectures. In NANOARCH '23: Proceedings of the 18th ACM International Symposium on Nanoscale Architectures (1-4). https://doi.org/10.1145/3611315.3633264

Proteinoids are peptide-like molecules that arise from the combination of amino acids in pre-biotic environments. Recent studies have revealed distinctive electrical characteristics of proteinoids, such as the presence of voltage-gated ion channels,... Read More about Electrical properties of proteinoids for unconventional computing architectures.

Light-induced spiking in proteinoids yields Boolean gates (2023)
Journal Article
Mougkogiannis, P., & Adamatzky, A. (2023). Light-induced spiking in proteinoids yields Boolean gates. Materials and Design, 236, Article 112460. https://doi.org/10.1016/j.matdes.2023.112460

This study analyzes light modulation of spiking in proteinoids, thermally condensed proteins exhibiting spike dynamics. We elucidate how light induces changes in proteinoids, modulating spike frequency. Results show proteinoids' spiking can be adjust... Read More about Light-induced spiking in proteinoids yields Boolean gates.

Learning in ensembles of proteinoid microspheres (2023)
Journal Article
Mougkogiannis, P., & Adamatzky, A. (2023). Learning in ensembles of proteinoid microspheres. Royal Society Open Science, 10(10), Article 230936. https://doi.org/10.1098/rsos.230936

Proteinoids are thermal proteins which form microspheres in water in the presence of salt. Ensembles of proteinoid microspheres exhibit passive nonlinear electrical properties and active neuron-like spiking of electrical potential. We propose that va... Read More about Learning in ensembles of proteinoid microspheres.

Logical gates in ensembles of proteinoid microspheres (2023)
Journal Article
Mougkogiannis, P., & Adamatzky, A. (2023). Logical gates in ensembles of proteinoid microspheres. PLoS ONE, 18(9), Article e0289433. https://doi.org/10.1371/journal.pone.0289433

Proteinoids are thermal proteins which swell into microspheres in aqueous solution. Ensembles of proteinoids produce electrical spiking activity similar to that of neurons. We introduce a novel method for implementing logical gates in the ensembles o... Read More about Logical gates in ensembles of proteinoid microspheres.

Proteinoid microspheres as protoneural networks (2023)
Journal Article
Mougkogiannis, P., & Adamatzky, A. (2023). Proteinoid microspheres as protoneural networks. ACS Omega, 8(38), 35417–35426. https://doi.org/10.1021/acsomega.3c05670

Proteinoids, also known as thermal proteins, possess a fascinating ability to generate microspheres that exhibit electrical spikes resembling the action potentials of neurons. These spiking microspheres, referred to as protoneurons, hold the potentia... Read More about Proteinoid microspheres as protoneural networks.

Light induced spiking of proteinoids (2023)
Journal Article
Mougkogiannis, P., & Adamatzky, A. (2023). Light induced spiking of proteinoids. BioSystems, 232, Article 105015. https://doi.org/10.1016/j.biosystems.2023.105015

Proteinoids, or thermal proteins, are produced by heating amino acids to their melting point and initiating polymerisation to produce polymeric chains. In aqueous solutions proteinoids swell into hollow microspheres. These microspheres produce endoge... Read More about Light induced spiking of proteinoids.

Transfer functions of proteinoid microspheres (2023)
Journal Article
Mougkogiannis, P., Phillips, N., & Adamatzky, A. (2023). Transfer functions of proteinoid microspheres. BioSystems, 227-228, https://doi.org/10.1016/j.biosystems.2023.104892

Proteinoids, or thermal proteins, are inorganic entities formed by heating amino acids to their melting point and commencing polymerisation to form polymeric chains. Typically, their diameters range from 1 μm to 10 μm. Some amino acids incorporated i... Read More about Transfer functions of proteinoid microspheres.

Low frequency electrical waves in ensembles of proteinoid microspheres (2023)
Journal Article
Mougkogiannis, P., & Adamatzky, A. (2023). Low frequency electrical waves in ensembles of proteinoid microspheres. Scientific Reports, 13(1), 1992. https://doi.org/10.1038/s41598-023-29067-0

Proteinoids (thermal proteins) are produced by heating amino acids to their melting point and initiation of polymerisation to produce polymeric chains. Amino acid-like molecules, or proteinoids, can condense at high temperatures to create aggregation... Read More about Low frequency electrical waves in ensembles of proteinoid microspheres.