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The relationship between adipose tissue skatole levels, rates of hepatic microsomal skatole metabolism and hepatic cytochrome P450IIE1 expression in two breeds of pig (2002)
Journal Article
Doran (nee Udovikova), O., Whittington, F., Wood, J. D., & McGivan, J. D. (2002). The relationship between adipose tissue skatole levels, rates of hepatic microsomal skatole metabolism and hepatic cytochrome P450IIE1 expression in two breeds of pig. Animal Science, 74(3), 461-468

The relationships between the level of skatole in backfat, the rate of skatole metabolism in isolated liver microsomes, hepatic cytochrome P450IIE1 content and mRNA levels were investigated in Large White ✕ Landrace (LW) and the Meishan ✕ Landrace... Read More about The relationship between adipose tissue skatole levels, rates of hepatic microsomal skatole metabolism and hepatic cytochrome P450IIE1 expression in two breeds of pig.

Mitochondria and cell death (2000)
Journal Article
Doran, E., Halestrap, A. P., Doran (nee Udovikova), O., Gillespie, J. P., & O'Toole, A. (2000). Mitochondria and cell death. Biochemical Society Transactions, 28(2), 170-177. https://doi.org/10.1042/bst0280170

Mitochondria play a central role in both apoptosis and necrosis through the opening of the mitochondrial permeability transition pore (MPTP). This is thought to be formed through a Ca2+-triggered conformational change of the adenine nucleotide transl... Read More about Mitochondria and cell death.

Mitochondria and cell death: a pore way to die? (2000)
Journal Article
Halestrap, A., Gillespie, J., O'Toole, A., & Doran (nee Udovikova), O. (2000). Mitochondria and cell death: a pore way to die?. Symposia- Society for Experimental Biology, 52, 65-80

Evidence that metformin exerts its anti-diabetic effects through inhibition of complex 1 of the mitochondrial respiratory chain (2000)
Journal Article
Owen, M., Doran (nee Udovikova), O., & Halestrap, A. (2000). Evidence that metformin exerts its anti-diabetic effects through inhibition of complex 1 of the mitochondrial respiratory chain. Biochemical Journal, 348(3), 607-614

Although metformin is widely used for the treatment of non-insulin-dependent diabetes, its mode of action remains unclear. Here we provide evidence that its primary site of action is through a direct inhibition of complex 1 of the respiratory chain.... Read More about Evidence that metformin exerts its anti-diabetic effects through inhibition of complex 1 of the mitochondrial respiratory chain.

Mitochondrial aldehyde reductase: Identification and characterization in rat liver and kidney cortex (1998)
Journal Article
Udovikova, E. A., Doran (nee Udovikova), O., & Wojtzcak, L. (1998). Mitochondrial aldehyde reductase: Identification and characterization in rat liver and kidney cortex. International Journal of Biochemistry and Cell Biology, 30(5), 597-608. https://doi.org/10.1016/S1357-2725%2897%2900143-X

Aldehyde reductase (EC 1.1.1.2) has been regarded so far as an exclusively cytosolic enzyme. The present investigation shows that mitochondria of rat liver, kidney cortex and, tentatively, heart also contain an enzyme catalyzing oxidation of NADPH by... Read More about Mitochondrial aldehyde reductase: Identification and characterization in rat liver and kidney cortex.

Effect of paracetamol on the microsomal oxidation, oxidative phosphorylation and liver mitochondria swelling in rats of various ages (1996)
Journal Article
Padalko, V. I., Doran (nee Udovikova), O., Kozlova, E., & Lemeshko, V. (1996). Effect of paracetamol on the microsomal oxidation, oxidative phosphorylation and liver mitochondria swelling in rats of various ages

The effect of hepatotoxic dose of paracetamol (800 mg per kg, intraperitoneally, once a day during two days) on the system of microsomal oxidation, respiration, oxidative phosphorylation and high amplitude swelling of liver mitochondria was studied o... Read More about Effect of paracetamol on the microsomal oxidation, oxidative phosphorylation and liver mitochondria swelling in rats of various ages.

The effect of osmotic pressure on oligomycin-sensitive ATPase activity and the liberation of Mg2+ from liver mitochondria of rats of various ages (1992)
Journal Article
Lemeshko, V. V., & Doran (nee Udovikova), O. (1992). The effect of osmotic pressure on oligomycin-sensitive ATPase activity and the liberation of Mg2+ from liver mitochondria of rats of various ages. Ukrainian Biochemical Journal, 61(4), 83-88

The influence of osmotic pressure of the incubating medium (25-500 mM sucrose) on oligomycin--sensitive, 2,4-dinitrophenyl-stimulated ATP-ase-activity, Mg2+ release and swelling of the liver mitochondria in 1-, 3-, 12-, 24-months Wistar rats is, inve... Read More about The effect of osmotic pressure on oligomycin-sensitive ATPase activity and the liberation of Mg2+ from liver mitochondria of rats of various ages.

Age-related differences in the effect of osmotic pressure on liver mitochondrial respiration in rats (1991)
Journal Article
Doran (nee Udovikova), O., & Lemeshko, V. V. (1991). Age-related differences in the effect of osmotic pressure on liver mitochondrial respiration in rats

The subject under investigation is the influence of osmotic pressure of incubation medium (25-500 mM of sucrose) upon the respiration and the respiration control (RC) of mitochondria of the liver of rats aged 1, 3, 12 and 24 months when oxidizing suc... Read More about Age-related differences in the effect of osmotic pressure on liver mitochondrial respiration in rats.