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All Outputs (7)

Equations to support redox experimentation (2019)
Book Chapter
Hancock, J. T., & Whiteman, M. Equations to support redox experimentation. In J. T. Hancock, & M. E. Conway (Eds.), Redox-Mediated Signal Transduction (183-195). Humana, New York, NY. https://doi.org/10.1007/978-1-4939-9463-2_15

© Springer Science+Business Media, LLC, part of Springer Nature 2019. Working with redox compounds needs to take into account the oxidation and reduction state of the compound under study. This redox state can be influenced by the media in which the... Read More about Equations to support redox experimentation.

Methods for the addition of redox compounds (2019)
Book Chapter
Hancock, J. T. Methods for the addition of redox compounds. In J. T. Hancock, & M. E. Conway (Eds.), Redox-Mediated Signal Transduction (13-25). Humana, New York, NY. https://doi.org/10.1007/978-1-4939-9463-2_2

© Springer Science+Business Media, LLC, part of Springer Nature 2019. Often in redox biology experiments there is a need to add compounds which impinge on the redox of the cellular environment cell. Such compounds may include reactive oxygen species... Read More about Methods for the addition of redox compounds.

Investigating ROS, RNS, and H2S-sensitive signaling proteins (2019)
Book Chapter
Williams, E., Whiteman, M., Wood, M. E., Wilson, I. D., Ladomery, M. R., Allainguillaume, J., …Hancock, J. T. (2019). Investigating ROS, RNS, and H2S-sensitive signaling proteins. In J. T. Hancock, & M. E. Conway (Eds.), Redox-Mediated Signal Transduction (27-42). Humana, New York, NY. https://doi.org/10.1007/978-1-4939-9463-2_3

© Springer Science+Business Media, LLC, part of Springer Nature 2019. The modification of proteins is a key way to alter their activity and function. Often thiols, cysteine residues, on proteins are attractive targets for such modification. Assuming... Read More about Investigating ROS, RNS, and H2S-sensitive signaling proteins.

Predicting the effects of low dose-rate ionizing radiation on redox potential in plant cells (2019)
Book Chapter
Caplin, N., & Willey, N. (2019). Predicting the effects of low dose-rate ionizing radiation on redox potential in plant cells. In J. T. Hancock, & M. E. Conway (Eds.), Redox-Mediated Signal Transduction, (135-142). New York, USA: Humana. https://doi.org/10.1007/978-1-4939-9463-2_11

During exposure of cells to acute high dose-rate ionizing radiation (IR), oxidants from the radiolysis of water can overwhelm antioxidant systems. Protecting flora from the effects of IR released from a nuclear industry of increasing global significa... Read More about Predicting the effects of low dose-rate ionizing radiation on redox potential in plant cells.

The role of redox in signal transduction (2019)
Book Chapter
Hancock, J. T. (2019). The role of redox in signal transduction. In J. T. Hancock, & M. E. Conway (Eds.), Redox-Mediated Signal Transduction (1-11). Humana, New York, NY. https://doi.org/10.1007/978-1-4939-9463-2_1

© Springer Science+Business Media, LLC, part of Springer Nature 2019. It is the functioning of efficient cell signaling which is vital for the survival of cells, whether it is a simple prokaryote or a complex eukaryote, including both animals and pla... Read More about The role of redox in signal transduction.

Aminotransferases (2011)
Book Chapter
Conway, M. E. (2011). Aminotransferases. In J. D'Mello (Ed.), Amino Acids in Human Nutrition and Health (24-41). CABI

The aminotransferases are PLP dependent proteins which catalyze the transfer of an amino group from the donor amino acid to α-ketoglutarate, forming glutamate and the respective keto acids. Several key aminotransferase proteins have been identified a... Read More about Aminotransferases.

Redox regulation and trapping sulfenic acid in the peroxide-sensitive human mitochondrial branched chain aminotransferase (2009)
Book Chapter
Hutson, S. M., Poole, L. B., Coles, S., & Conway, M. E. (2009). Redox regulation and trapping sulfenic acid in the peroxide-sensitive human mitochondrial branched chain aminotransferase. In J. T. Hancock (Ed.), Redox-Mediated Signal Transduction (135-148). Humana Press (Springer Imprint). https://doi.org/10.1007/978-1-59745-129-1_10

The human branched chain aminotransferase enzymes are key regulators of glutamate metabolism in the brain and are among a growing number of redox-sensitive proteins. Studies that use thiol-specific reagents and electrospray ionization mass spectromet... Read More about Redox regulation and trapping sulfenic acid in the peroxide-sensitive human mitochondrial branched chain aminotransferase.