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All Outputs (148)

Which elements of hospital-based clinical decision support tools for the assessment and management of children with head injury can be adapted for use by paramedics in prehospital care? A systematic mapping review and narrative synthesis (2024)
Journal Article
Proctor, A., Lyttle, M., Billing, J., Shaw, P., Simpson, J., Voss, S., & Benger, J. R. (2024). Which elements of hospital-based clinical decision support tools for the assessment and management of children with head injury can be adapted for use by paramedics in prehospital care? A systematic mapping review and narrative synthesis. BMJ Open, 14(2), Article e078363. https://doi.org/10.1136/bmjopen-2023-078363

Objective Hospital-based clinical decision tools support clinician decision-making when a child presents to the emergency department with a head injury, particularly regarding CT scanning. However, there is no decision tool to support prehospital cli... Read More about Which elements of hospital-based clinical decision support tools for the assessment and management of children with head injury can be adapted for use by paramedics in prehospital care? A systematic mapping review and narrative synthesis.

The clinical impact of serious respiratory disease in children under the age of two years during the 2021-2022 bronchiolitis season in England, Scotland and Ireland (2023)
Journal Article
Williams, T. C., Marlow, R., Hardelid, P., Lyttle, M. D., Lewis, K. M., Mpamhanga, C. D., …Roland, D. (in press). The clinical impact of serious respiratory disease in children under the age of two years during the 2021-2022 bronchiolitis season in England, Scotland and Ireland. Journal of Infectious Diseases, https://doi.org/10.1093/infdis/jiad551

Interventions introduced to reduce the spread of SARS-CoV-2 led to a widespread reduction in childhood infections. However, from spring 2021 onwards the United Kingdom and Ireland experienced an unusual out-of-season epidemic of respiratory disease.... Read More about The clinical impact of serious respiratory disease in children under the age of two years during the 2021-2022 bronchiolitis season in England, Scotland and Ireland.

Core outcomes and factors influencing the experience of care for children with severe acute exacerbations of asthma: A qualitative study (2023)
Journal Article
Craig, S., Xu, Y., Robas, K., Iramain, R., Yock-Corrales, A., Soto-Martinez, M. E., …Babl, F. E. (2023). Core outcomes and factors influencing the experience of care for children with severe acute exacerbations of asthma: A qualitative study. BMJ Open Respiratory Research, 10(1), Article e001723. https://doi.org/10.1136/bmjresp-2023-001723

Objective To identify the outcomes considered important, and factors influencing the patient experience, for parents and caregivers of children presenting to hospital with a severe acute exacerbation of asthma. This work contributes to the outcome-id... Read More about Core outcomes and factors influencing the experience of care for children with severe acute exacerbations of asthma: A qualitative study.

Applying clinical decision aids for the assessment and management of febrile infants presenting to emergency care in the UK and Ireland: Febrile Infant Diagnostic Assessment and Outcome (FIDO) Study protocol (2023)
Journal Article
Umana, E., Mills, C., Norman-Bruce, H., Wilson, K., Mitchell, H., Mcfetridge, L., …Waterfield, T. (2023). Applying clinical decision aids for the assessment and management of febrile infants presenting to emergency care in the UK and Ireland: Febrile Infant Diagnostic Assessment and Outcome (FIDO) Study protocol. BMJ Open, 13(9), Article e075823. https://doi.org/10.1136/bmjopen-2023-075823

Introduction Febrile infants 90 days and younger are at risk of invasive bacterial infections (bacteraemia and meningitis) and urinary tract infections. Together this is previously termed serious bacterial infection with an incidence of approximately... Read More about Applying clinical decision aids for the assessment and management of febrile infants presenting to emergency care in the UK and Ireland: Febrile Infant Diagnostic Assessment and Outcome (FIDO) Study protocol.

Comparison of injury patterns and interventions between adolescent, adult and paediatric trauma cases: A cross-sectional review of TARN data (2023)
Journal Article
Mullen, S., Tolson, A., Bouamra, O., Watson, B., Lyttle, M. D., Roland, D., & James, D. (2023). Comparison of injury patterns and interventions between adolescent, adult and paediatric trauma cases: A cross-sectional review of TARN data. BMJ Open, 13(5), Article e064101. https://doi.org/10.1136/bmjopen-2022-064101

Objectives The aim is to compare adolescent (10-24.99 years) trauma patterns and interventions to adult (≥25) and paediatric cases (

A diagnostic accuracy study to evaluate standard rapid diagnostic test (RDT) alone to safely rule out imported malaria in children presenting to UK emergency departments (2023)
Journal Article
Bird, C., Hayward, G. N., Turner, P. J., Merrick, V., Lyttle, M. D., Mullen, N., & Fanshawe, T. R. (2023). A diagnostic accuracy study to evaluate standard rapid diagnostic test (RDT) alone to safely rule out imported malaria in children presenting to UK emergency departments. Journal of the Pediatric Infectious Diseases Society, 12(5), 290-297. https://doi.org/10.1093/jpids/piad024

BACKGROUND: Microscopy is the gold standard for malaria diagnosis but is dependent on trained personnel. Rapid diagnostic tests (RDTs) form the mainstay of diagnosis in endemic areas without access to high-quality microscopy. We aimed to evaluate whe... Read More about A diagnostic accuracy study to evaluate standard rapid diagnostic test (RDT) alone to safely rule out imported malaria in children presenting to UK emergency departments.

Factors related to adverse long-term outcomes after mild traumatic brain injury in children: A scoping review (2023)
Journal Article
Ijaz, S., Scott, L., Dawson, S., Wilson, R., Jackson, J., Birnie, K., …Mytton, J. (in press). Factors related to adverse long-term outcomes after mild traumatic brain injury in children: A scoping review. Archives of Disease in Childhood, 108(6), 492-497. https://doi.org/10.1136/archdischild-2022-325202

Objective: To identify demographic, premorbid and injury-related factors, or biomarkers associated with long-term (≥3 months) adverse outcomes in children after mild traumatic brain injury (mTBI). Design: Scoping review of literature. Patients: Child... Read More about Factors related to adverse long-term outcomes after mild traumatic brain injury in children: A scoping review.

International perspective on research priorities and outcome measures of importance in the care of children with acute exacerbations of asthma: A qualitative interview study (2023)
Journal Article
Gray, C. S., Xu, Y., Babl, F. E., Dalziel, S., Powell, C. V., Chong, S., …Craig, S. (2023). International perspective on research priorities and outcome measures of importance in the care of children with acute exacerbations of asthma: A qualitative interview study. BMJ Open Respiratory Research, 10(1), Article e001502. https://doi.org/10.1136/bmjresp-2022-001502

Background: Acute exacerbations of asthma are common in children, however, treatment decisions for severe exacerbations are challenging due to a lack of robust evidence. In order to create more robust research, a core set of outcome measures needs to... Read More about International perspective on research priorities and outcome measures of importance in the care of children with acute exacerbations of asthma: A qualitative interview study.

Assessment and management of children with head injury: Practice and opinion (2023)
Journal Article
Proctor, A., Voss, S., Lyttle, M., & Benger, J. (2023). Assessment and management of children with head injury: Practice and opinion. Journal of Paramedic Practice, 15(2), 58-64. https://doi.org/10.12968/jpar.2023.15.2.58

Background: Head injury is common in children with approximately 700 000 attendances at emergency departments annually; one-third are conveyed by ambulance. However, 75% of them are discharged with no treatment. Most head-injured children could be ma... Read More about Assessment and management of children with head injury: Practice and opinion.

The journey back to normality: Support systems and posttrauma needs following exposure to single-incident trauma among children and adolescents (2023)
Journal Article
Haag, K., Hiller, R., McGuire, R., Lyttle, M., & Halligan, S. L. (2023). The journey back to normality: Support systems and posttrauma needs following exposure to single-incident trauma among children and adolescents. Journal of Traumatic Stress, 36(1), 218-229. https://doi.org/10.1002/jts.22902

Social support has been linked to posttrauma adjustment in children and adolescents, but the components of good support remain poorly defined. We conducted qualitative interviews with 30 youths aged 7–16 years after being admitted to a hospital follo... Read More about The journey back to normality: Support systems and posttrauma needs following exposure to single-incident trauma among children and adolescents.

A systematic literature review of the relationship between parenting responses and child post-traumatic stress symptoms (2022)
Journal Article
Afzal, N., Ye, S., Page, A. C., Trickey, D., Lyttle, M. D., Hiller, R. M., & Halligan, S. L. (2023). A systematic literature review of the relationship between parenting responses and child post-traumatic stress symptoms. European Journal of Psychotraumatology, 14(1), Article 2156053. https://doi.org/10.1080/20008066.2022.2156053

Background: Parents are a key source of support for children exposed to single-incident/acute traumas and can thereby play a potentially significant role in children’s post-trauma psychological adjustment. However, the evidence base examining parenta... Read More about A systematic literature review of the relationship between parenting responses and child post-traumatic stress symptoms.

International variation in evidence-based emergency department management of bronchiolitis: a retrospective cohort study (2022)
Journal Article
Lirette, M., Kuppermann, N., Finkelstein, Y., Zemek, R., Plint, A. C., Florin, T. A., …Schuh, S. (2022). International variation in evidence-based emergency department management of bronchiolitis: a retrospective cohort study. BMJ Open, 12(12), e059784. https://doi.org/10.1136/bmjopen-2021-059784

OBJECTIVES: We aimed to evaluate the international variation in the use of evidence-based management (EBM) in bronchiolitis. We hypothesised that management consistent with full-EBM practices is associated with the research network of care, adjusted... Read More about International variation in evidence-based emergency department management of bronchiolitis: a retrospective cohort study.

Incidence of traumatic brain injuries in head-injured children with seizures (2022)
Journal Article
Borland, M. L., Dalziel, S. R., Phillips, N., Dalton, S., Lyttle, M. D., Bressan, S., …Babl, F. E. (2023). Incidence of traumatic brain injuries in head-injured children with seizures. Emergency Medicine Australasia, 35(2), 289-296. https://doi.org/10.1111/1742-6723.14112

Objective: Incidence and short-term outcomes of clinically important traumatic brain injury (ciTBI) in head-injured children presenting to ED with post-traumatic seizure (PTS) is not described in current literature. Methods: Planned secondary analysi... Read More about Incidence of traumatic brain injuries in head-injured children with seizures.

Educational interventions to prevent paediatric abusive head trauma in babies younger than one year old: A systematic review and meta-analyses (2022)
Journal Article
Scott, L. J., Wilson, R., Davies, P., Lyttle, M. D., Mytton, J., Dawson, S., …Savović, J. (2022). Educational interventions to prevent paediatric abusive head trauma in babies younger than one year old: A systematic review and meta-analyses. Child Abuse and Neglect, 134, 105935. https://doi.org/10.1016/j.chiabu.2022.105935

Background: Paediatric abusive head trauma (AHT) occurs in young children due to violent shaking or blunt impact. Educational and behavioural programmes modifying parent/infant interactions may aid primary prevention. This systematic review aims to a... Read More about Educational interventions to prevent paediatric abusive head trauma in babies younger than one year old: A systematic review and meta-analyses.

Paediatric major incident triage: A Delphi process to determine clinicians' attitudes and beliefs within the United Kingdom and Ireland (2022)
Journal Article
Vassallo, J., Blakey, S., Cowburn, P., Surridge, J., Smith, J. E., Scholefield, B., …(Paediatric Emergency Research in the UK and Ireland), P. (2023). Paediatric major incident triage: A Delphi process to determine clinicians' attitudes and beliefs within the United Kingdom and Ireland. Acta Paediatrica, 112(1), 154-161. https://doi.org/10.1111/apa.16567

Aim: Triage is key to effective management of major incidents, yet there is scarce evidence surrounding the optimal method of paediatric major incident triage (MIT). This study aimed to derive consensus on key components of paediatric MIT among healt... Read More about Paediatric major incident triage: A Delphi process to determine clinicians' attitudes and beliefs within the United Kingdom and Ireland.

Features of the transposed seasonality of the 2021 RSV epidemic in the UK and Ireland: analysis of the first 10 000 patients (2022)
Journal Article
Roland, D., Williams, T., Lyttle, M. D., Marlow, R., Hardelid, P., Sinha, I., …Cunningham, S. (2022). Features of the transposed seasonality of the 2021 RSV epidemic in the UK and Ireland: analysis of the first 10 000 patients. Archives of Disease in Childhood, 107(11), 1062-1063. https://doi.org/10.1136/archdischild-2022-324241

Non-pharmaceutical interventions (NPIs) introduced globally to limit the spread of SARS-CoV-2 led to disruption of the typical respiratory syncytial virus (RSV) seasonality.1 Studies examining the resurgence of RSV have been limited by sample size an... Read More about Features of the transposed seasonality of the 2021 RSV epidemic in the UK and Ireland: analysis of the first 10 000 patients.

Presentations of children to emergency departments across Europe and the COVID-19 pandemic: A multinational observational study (2022)
Journal Article
Nijman, R. G., Honeyford, K., Farrugia, R., Rose, K., Bognar, Z., Buonsenso, D., …Titomanlio, L. (2022). Presentations of children to emergency departments across Europe and the COVID-19 pandemic: A multinational observational study. PLoS Medicine, 19(8), e1003974. https://doi.org/10.1371/journal.pmed.1003974

BACKGROUND: During the initial phase of the Coronavirus Disease 2019 (COVID-19) pandemic, reduced numbers of acutely ill or injured children presented to emergency departments (EDs). Concerns were raised about the potential for delayed and more sever... Read More about Presentations of children to emergency departments across Europe and the COVID-19 pandemic: A multinational observational study.

Diagnostic test accuracy of dipstick urinalysis for diagnosing urinary tract infection in febrile infants attending the emergency department (2022)
Journal Article
Waterfield, T., Foster, S., Platt, R., Barrett, M. J., Durnin, S., Maney, J., …Lyttle, M. D. (2022). Diagnostic test accuracy of dipstick urinalysis for diagnosing urinary tract infection in febrile infants attending the emergency department. Archives of Disease in Childhood, 107(12), 1095-1099. https://doi.org/10.1136/archdischild-2022-324300

OBJECTIVE: To report the diagnostic test accuracy of dipstick urinalysis for the detection of urinary tract infections (UTIs) in febrile infants aged 90 days or less attending the emergency department (ED). DESIGN: Retrospective cohort study. PATIENT... Read More about Diagnostic test accuracy of dipstick urinalysis for diagnosing urinary tract infection in febrile infants attending the emergency department.

Barriers to emergency department clinicians' confidence in providing paediatric trauma‐informed care (2022)
Journal Article
Afzal, N., Lyttle, M. D., Alisic, E., Trickey, D., Hiller, R. M., & Halligan, S. L. (2022). Barriers to emergency department clinicians' confidence in providing paediatric trauma‐informed care. JCPP Advances, 2(3), e12091. https://doi.org/10.1002/jcv2.12091

Abstract: Background: It has been estimated that around 31% of children will experience a traumatic event during childhood, most commonly serious accidents that lead to hospitalisation. Around 15% of children who experience such events go onto develo... Read More about Barriers to emergency department clinicians' confidence in providing paediatric trauma‐informed care.

Pain management in children and young adults with minor injury in emergency departments in the UK and Ireland: A PERUKI service evaluation (2022)
Journal Article
Hartshorn, S., Durnin, S., Lyttle, M. D., & Barrett, M. (2022). Pain management in children and young adults with minor injury in emergency departments in the UK and Ireland: A PERUKI service evaluation. BMJ Paediatrics Open, 6(1), Article e001273. https://doi.org/10.1136/bmjpo-2021-001273

Background Management of acute pain should commence at the earliest opportunity, as it has many short-term and long-term consequences. A research priority of Paediatric Emergency Research in the UK and Ireland (PERUKI) was to examine paediatric pain... Read More about Pain management in children and young adults with minor injury in emergency departments in the UK and Ireland: A PERUKI service evaluation.