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A survey examining the use of mechanical insufflation-exsufflation on adult intensive care units across the UK (2019)
Journal Article
Cramp, F., Swingwood, E., & Tume, L. (in press). A survey examining the use of mechanical insufflation-exsufflation on adult intensive care units across the UK. Journal of the Intensive Care Society, https://doi.org/10.1177/1751143719870121

© The Intensive Care Society 2019. Introduction: Despite potential benefits, it is not known how widely physiotherapists use mechanical insufflation-exsufflation devices on UK adult intensive care units. This survey aimed to describe mechanical insuf... Read More about A survey examining the use of mechanical insufflation-exsufflation on adult intensive care units across the UK.

Nutritional status deterioration occurs frequently during childrens’ intensive care unit stay (2019)
Journal Article
Valla, F. V., Baudin, F., Gaillard Le Roux, B., Ford-Chessel, C., Gervet, E., Giraud, C., …Tume, L. (2019). Nutritional status deterioration occurs frequently during childrens’ intensive care unit stay. Pediatric Critical Care Medicine, 20(8), 714-721. https://doi.org/10.1097/PCC.0000000000001979

OBJECTIVES: Malnutrition and faltering growth at PICU admission have been related to suboptimal outcomes. However, little is known about nutritional status deterioration during PICU stay, as critical illness is characterized by a profound and complex... Read More about Nutritional status deterioration occurs frequently during childrens’ intensive care unit stay.

Do infants with transposition of the great arteries born outside a specialist centre have different outcomes? (2019)
Journal Article
Tume, L. N., Hunt, R., Veal, C., & Tume, L. N. (2019). Do infants with transposition of the great arteries born outside a specialist centre have different outcomes?. Cardiology in the Young, 29(8), 1030-1035. https://doi.org/10.1017/S1047951119001367

© Cambridge University Press 2019. Background: Infants born with undiagnosed transposition of the great arteries continue to be born in district general hospitals despite the improvements made in antenatal scanning. Evidence indicates improved outcom... Read More about Do infants with transposition of the great arteries born outside a specialist centre have different outcomes?.

Where Should Critically Ill Adolescents Receive Care? A Qualitative Interview-Based Study of Perspectives of Staff Working in Adult and Pediatric Intensive Care Units (2019)
Journal Article
Wood, D., Geoghegan, S., Ramnarayan, P., Davis, P. J., Tume, L., Pappachan, J. V., …Wray, J. (in press). Where Should Critically Ill Adolescents Receive Care? A Qualitative Interview-Based Study of Perspectives of Staff Working in Adult and Pediatric Intensive Care Units. Journal of Intensive Care Medicine, https://doi.org/10.1177/0885066619856573

© The Author(s) 2019. Purpose: In the United Kingdom, critically ill adolescents are treated in either adult or pediatric intensive care units (AICUs or PICUs). This study explores staff perspectives on where and how best to care for this distinct gr... Read More about Where Should Critically Ill Adolescents Receive Care? A Qualitative Interview-Based Study of Perspectives of Staff Working in Adult and Pediatric Intensive Care Units.

Parents’ prioritised outcomes for trials investigating treatments for paediatric severe infection: A qualitative synthesis (2019)
Journal Article
Woolfall, K., O'Hara, C., Deja, E., Canter, R., Khan, I., Mouncey, P., …Inwald, D. (2019). Parents’ prioritised outcomes for trials investigating treatments for paediatric severe infection: A qualitative synthesis. Archives of Disease in Childhood, 104(11), 1077-1082. https://doi.org/10.1136/archdischild-2019-316807

Objective: To identify parents' prioritised outcomes by combining qualitative findings from two trial feasibility studies of interventions for paediatric suspected severe infection. Design: Qualitative synthesis combining parent interview data from t... Read More about Parents’ prioritised outcomes for trials investigating treatments for paediatric severe infection: A qualitative synthesis.

Validity and effectiveness of paediatric early warning systems and track and trigger tools for identifying and reducing clinical deterioration in hospitalised children: A systematic review (2019)
Journal Article
Trubey, R., Huang, C., Lugg-Widger, F. V., Hood, K., Allen, D., Edwards, D., …Powell, C. (2019). Validity and effectiveness of paediatric early warning systems and track and trigger tools for identifying and reducing clinical deterioration in hospitalised children: A systematic review. BMJ Open, 9(5), https://doi.org/10.1136/bmjopen-2018-022105

Objective: To assess (1) how well validated existing paediatric track and trigger tools (PTTT) are for predicting adverse outcomes in hospitalised children, and (2) how effective broader paediatric early warning systems are at reducing adverse outcom... Read More about Validity and effectiveness of paediatric early warning systems and track and trigger tools for identifying and reducing clinical deterioration in hospitalised children: A systematic review.

Gastric residual volume measurement in UK paediatric intensive care units: A survey of practice (2019)
Journal Article
Tume, L., Arch, B., Woolfall, K., Latten, L., Deja, E., Roper, L., …Dorling, J. (2019). Gastric residual volume measurement in UK paediatric intensive care units: A survey of practice. Pediatric Critical Care Medicine, 20(8), 707-713. https://doi.org/10.1097/PCC.0000000000001944

Objective: Despite little evidence, the practice of routine measurement of gastric residual volume to guide both the initiation and delivery of enteral feeding in pediatric intensive care units is widespread internationally. In light of increased scr... Read More about Gastric residual volume measurement in UK paediatric intensive care units: A survey of practice.

Permissive versus restrictive temperature thresholds in critically ill children with fever and infection: A multicentre randomized clinical pilot trial (2019)
Journal Article
Peters, M. J., Woolfall, K., Khan, I., Deja, E., Mouncey, P. R., Wulff, J., …Rowan, K. M. (2019). Permissive versus restrictive temperature thresholds in critically ill children with fever and infection: A multicentre randomized clinical pilot trial. Critical Care, 23(1), https://doi.org/10.1186/s13054-019-2354-4

Background: Fever improves pathogen control at a significant metabolic cost. No randomized clinical trials (RCT) have compared fever treatment thresholds in critically ill children. We performed a pilot RCT to determine whether a definitive trial of... Read More about Permissive versus restrictive temperature thresholds in critically ill children with fever and infection: A multicentre randomized clinical pilot trial.

NUTRI-REAPED study: nutritional assessment of French critically ill children and nutrition practice survey in French-speaking pediatric intensive care units (2019)
Journal Article
Jacquot, A., Valla, F. V., Mura, T., Tume, L. N., Bertet, H., Ford-Chessel, C., …Gaillard-Le Roux, B. (2019). NUTRI-REAPED study: nutritional assessment of French critically ill children and nutrition practice survey in French-speaking pediatric intensive care units. Annals of Intensive Care, 9(1), https://doi.org/10.1186/s13613-019-0493-z

© 2019, The Author(s). Background: Impaired nutritional status is adversely associated with suboptimal outcomes in critically ill children. Undernutrition at pediatric intensive care unit (PICU) admission ranges from 15 to 65%. A lack of knowledge of... Read More about NUTRI-REAPED study: nutritional assessment of French critically ill children and nutrition practice survey in French-speaking pediatric intensive care units.

Priorities for nutrition research in pediatric critical care (2018)
Journal Article
Tume, L. N., Valla, F. V., Floh, A., Goday, P., Jotterand Chaparro, C., Larsen, B., …Mehta, N. (2019). Priorities for nutrition research in pediatric critical care. Journal of Parenteral and Enteral Nutrition, 43(7), 853-862. https://doi.org/10.1002/jpen.1498

Background: Widespread variation exists in pediatric critical care nutrition practices, largely because of the scarcity of evidence to guide best practice recommendations. Objective: The objective of this paper was to develop a list of topics to b... Read More about Priorities for nutrition research in pediatric critical care.

Nutritional management of young infants presenting with acute bronchiolitis in Belgium, France and Switzerland: Survey of current practices and documentary search of national guidelines worldwide (2018)
Journal Article
Valla, F. V., Baudin, F., Demaret, P., Rooze, S., Moullet, C., Cotting, J., …Le Roux, B. G. (2019). Nutritional management of young infants presenting with acute bronchiolitis in Belgium, France and Switzerland: Survey of current practices and documentary search of national guidelines worldwide. European Journal of Pediatrics, 178(3), 331-340. https://doi.org/10.1007/s00431-018-3300-1

© 2018, Springer-Verlag GmbH Germany, part of Springer Nature. Feeding difficulties are common in young infants presenting with acute bronchiolitis, but limited data is available to guide clinicians adapting nutritional management. We aimed to assess... Read More about Nutritional management of young infants presenting with acute bronchiolitis in Belgium, France and Switzerland: Survey of current practices and documentary search of national guidelines worldwide.

Parent's experiences of their child's withdrawal syndrome: A driver for reciprocal nurse-parent partnership in withdrawal assessment (2018)
Journal Article
Craske, J., Carter, B., Jarman, I., & Tume, L. (2019). Parent's experiences of their child's withdrawal syndrome: A driver for reciprocal nurse-parent partnership in withdrawal assessment. Intensive and Critical Care Nursing, 50, 71-78. https://doi.org/10.1016/j.iccn.2018.09.001

© 2018 Elsevier Ltd Withdrawal assessment in critically ill children is complicated by the reliance on non-specific behaviours and compounded when the child's typical behaviours are unknown. The existing approach to withdrawal assessment assumes that... Read More about Parent's experiences of their child's withdrawal syndrome: A driver for reciprocal nurse-parent partnership in withdrawal assessment.

A review of feeding intolerance in critically ill children (2018)
Journal Article
Tume, L. N., & Valla, F. V. (2018). A review of feeding intolerance in critically ill children. European Journal of Pediatrics, 177(11), 1675-1683. https://doi.org/10.1007/s00431-018-3229-4

© 2018, The Author(s). Ensuring optimal nutrition is vital in critically ill children and enteral feeding is the main route of delivery in intensive care. Feeding intolerance is the most commonly cited reason amongst pediatric intensive care unit hea... Read More about A review of feeding intolerance in critically ill children.

A prospective, mixed-methods, before and after study to identify the evidence base for the core components of an effective Paediatric Early Warning System and the development of an implementation package containing those core recommendations for use in th (2018)
Journal Article
Thomas-Jones, E., Lloyd, A., Roland, D., Sefton, G., Tume, L. N., Hood, K., …Powell, C. (2018). A prospective, mixed-methods, before and after study to identify the evidence base for the core components of an effective Paediatric Early Warning System and the development of an implementation package containing those core recommendations for use in the UK: Paediatric early warning system - utilisation and mortality avoidance- the PUMA study protocol. BMC Pediatrics, 18(1), 244. https://doi.org/10.1186/s12887-018-1210-z

© 2018 The Author(s). Background: In hospital, staff need to routinely monitor patients to identify those who are seriously ill, so that they receive timely treatment to improve their condition. A Paediatric Early Warning System is a multi-faceted so... Read More about A prospective, mixed-methods, before and after study to identify the evidence base for the core components of an effective Paediatric Early Warning System and the development of an implementation package containing those core recommendations for use in th.

Newly qualified Saudi nurses' ability to recognise the deteriorating child in hospital (2018)
Journal Article
Al-Thubaity, D., Williamson, S., Leavey, R., & Tume, L. N. (2019). Newly qualified Saudi nurses' ability to recognise the deteriorating child in hospital. Nursing in Critical Care, 24(5), 263-267. https://doi.org/10.1111/nicc.12356

Background: It is recognized that nurses' failure to recognize and respond promptly to deterioration in children's physiological status can result in increased morbidity and mortality. Aim: The aim of this study was to explore the ability of Saudi-ed... Read More about Newly qualified Saudi nurses' ability to recognise the deteriorating child in hospital.

Enteral Feeding Practices in Infants with Congenital Heart Disease Across European PICUs: A European Society of Pediatric and Neonatal Intensive Care Survey (2017)
Journal Article
Tume, L. N., Balmaks, R., Latten, L., Da Cruz, E., Verbruggen, S., & Valla, F. (2018). Enteral Feeding Practices in Infants with Congenital Heart Disease Across European PICUs: A European Society of Pediatric and Neonatal Intensive Care Survey. Pediatric Critical Care Medicine, 19(2), 137-144. https://doi.org/10.1097/PCC.0000000000001412

© Copyright 2017 by the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies. Objectives: To describe enteral feeding practices in pre and postoperative infants with congenital heart disease in... Read More about Enteral Feeding Practices in Infants with Congenital Heart Disease Across European PICUs: A European Society of Pediatric and Neonatal Intensive Care Survey.

Routine gastric residual volume measurement and energy target achievement in the PICU: A comparison study (2017)
Journal Article
Lefèvre, M. H., Tume, L. N., Bickerdike, A., Latten, L., Davies, S., Nicolas, G. W., & Valla, F. (2017). Routine gastric residual volume measurement and energy target achievement in the PICU: A comparison study. European Journal of Pediatrics, 176(12), 1637-1644. https://doi.org/10.1007/s00431-017-3015-8

Critically ill children frequently fail to achieve adequate energy intake and some care practices, such as the measurement of gastric residual volume (GRV) may contribute to this problem. We compared outcomes in two similar European Pediatric Intensi... Read More about Routine gastric residual volume measurement and energy target achievement in the PICU: A comparison study.

Patterns of instability associated with endotracheal suctioning in infants with singleventricle physiology (2017)
Journal Article
Phys, G. D., Guerrero, R., Baines, P., Tume, L. N., Johnson, R., Ritson, P., …Walsh, L. (2017). Patterns of instability associated with endotracheal suctioning in infants with singleventricle physiology. American Journal of Critical Care, 26(5), 388-394. https://doi.org/10.4037/ajcc2017844

© 2017 American Association of Critical-Care Nurses. Background In infants with single-ventricle physiology, endotracheal suctioning poses risks because of the instability between pulmonary and systemic blood flow. Objective To examine processes and... Read More about Patterns of instability associated with endotracheal suctioning in infants with singleventricle physiology.

Paediatric intensive care nurses' decision-making around gastric residual volume measurement (2017)
Journal Article
Tume, L. N., Tume, L. N., Latten, L., & Kenworthy, L. (2017). Paediatric intensive care nurses' decision-making around gastric residual volume measurement. Nursing in Critical Care, 22(5), 293-297. https://doi.org/10.1111/nicc.12304

© 2017 British Association of Critical Care Nurses Background: Measuring gastric residual volume (GRV) to guide enteral feeding is a common nursing practice in intensive care units, yet little evidence supports this practice. In addition, this practi... Read More about Paediatric intensive care nurses' decision-making around gastric residual volume measurement.


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