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A survey examining the use of mechanical insufflation-exsufflation on adult intensive care units across the UK (2019)
Journal Article
Cramp, F., Swingwood, E., & Tume, L. (2020). A survey examining the use of mechanical insufflation-exsufflation on adult intensive care units across the UK. Journal of the Intensive Care Society, 21(4), 283-289. https://doi.org/10.1177/1751143719870121

Introduction: Despite potential benefits, it is not known how widely physiotherapists use mechanical insufflation-exsufflation devices on UK adult intensive care units. This survey aimed to describe mechanical insufflation-exsufflation use in UK adul... Read More about A survey examining the use of mechanical insufflation-exsufflation on adult intensive care units across the UK.

Nutritional status deterioration occurs frequently during childrens’ intensive care unit stay (2019)
Journal Article
Valla, F. V., Baudin, F., Gaillard Le Roux, B., Ford-Chessel, C., Gervet, E., Giraud, C., …Tume, L. (2019). Nutritional status deterioration occurs frequently during childrens’ intensive care unit stay. Pediatric Critical Care Medicine, 20(8), 714-721. https://doi.org/10.1097/PCC.0000000000001979

OBJECTIVES: Malnutrition and faltering growth at PICU admission have been related to suboptimal outcomes. However, little is known about nutritional status deterioration during PICU stay, as critical illness is characterized by a profound and complex... Read More about Nutritional status deterioration occurs frequently during childrens’ intensive care unit stay.

Do infants with transposition of the great arteries born outside a specialist centre have different outcomes? (2019)
Journal Article
Tume, L. N., Hunt, R., Veal, C., & Tume, L. N. (2019). Do infants with transposition of the great arteries born outside a specialist centre have different outcomes?. Cardiology in the Young, 29(8), 1030-1035. https://doi.org/10.1017/S1047951119001367

© Cambridge University Press 2019. Background: Infants born with undiagnosed transposition of the great arteries continue to be born in district general hospitals despite the improvements made in antenatal scanning. Evidence indicates improved outcom... Read More about Do infants with transposition of the great arteries born outside a specialist centre have different outcomes?.

Where Should Critically Ill Adolescents Receive Care? A Qualitative Interview-Based Study of Perspectives of Staff Working in Adult and Pediatric Intensive Care Units (2019)
Journal Article
Wood, D., Geoghegan, S., Ramnarayan, P., Davis, P. J., Tume, L., Pappachan, J. V., …Wray, J. (2020). Where Should Critically Ill Adolescents Receive Care? A Qualitative Interview-Based Study of Perspectives of Staff Working in Adult and Pediatric Intensive Care Units. Journal of Intensive Care Medicine, 35(11), 1271-1277. https://doi.org/10.1177/0885066619856573

Purpose: In the United Kingdom, critically ill adolescents are treated in either adult or pediatric intensive care units (AICUs or PICUs). This study explores staff perspectives on where and how best to care for this distinct group. Materials and Met... Read More about Where Should Critically Ill Adolescents Receive Care? A Qualitative Interview-Based Study of Perspectives of Staff Working in Adult and Pediatric Intensive Care Units.

Parents’ prioritised outcomes for trials investigating treatments for paediatric severe infection: A qualitative synthesis (2019)
Journal Article
Woolfall, K., O'Hara, C., Deja, E., Canter, R., Khan, I., Mouncey, P., …Inwald, D. (2019). Parents’ prioritised outcomes for trials investigating treatments for paediatric severe infection: A qualitative synthesis. Archives of Disease in Childhood, 104(11), 1077-1082. https://doi.org/10.1136/archdischild-2019-316807

Objective: To identify parents' prioritised outcomes by combining qualitative findings from two trial feasibility studies of interventions for paediatric suspected severe infection. Design: Qualitative synthesis combining parent interview data from t... Read More about Parents’ prioritised outcomes for trials investigating treatments for paediatric severe infection: A qualitative synthesis.

Validity and effectiveness of paediatric early warning systems and track and trigger tools for identifying and reducing clinical deterioration in hospitalised children: A systematic review (2019)
Journal Article
Trubey, R., Huang, C., Lugg-Widger, F. V., Hood, K., Allen, D., Edwards, D., …Powell, C. (2019). Validity and effectiveness of paediatric early warning systems and track and trigger tools for identifying and reducing clinical deterioration in hospitalised children: A systematic review. BMJ Open, 9(5), https://doi.org/10.1136/bmjopen-2018-022105

Objective: To assess (1) how well validated existing paediatric track and trigger tools (PTTT) are for predicting adverse outcomes in hospitalised children, and (2) how effective broader paediatric early warning systems are at reducing adverse outcom... Read More about Validity and effectiveness of paediatric early warning systems and track and trigger tools for identifying and reducing clinical deterioration in hospitalised children: A systematic review.

Gastric residual volume measurement in UK paediatric intensive care units: A survey of practice (2019)
Journal Article
Tume, L., Arch, B., Woolfall, K., Latten, L., Deja, E., Roper, L., …Dorling, J. (2019). Gastric residual volume measurement in UK paediatric intensive care units: A survey of practice. Pediatric Critical Care Medicine, 20(8), 707-713. https://doi.org/10.1097/PCC.0000000000001944

Objective: Despite little evidence, the practice of routine measurement of gastric residual volume to guide both the initiation and delivery of enteral feeding in pediatric intensive care units is widespread internationally. In light of increased scr... Read More about Gastric residual volume measurement in UK paediatric intensive care units: A survey of practice.

Permissive versus restrictive temperature thresholds in critically ill children with fever and infection: A multicentre randomized clinical pilot trial (2019)
Journal Article
Peters, M. J., Woolfall, K., Khan, I., Deja, E., Mouncey, P. R., Wulff, J., …Rowan, K. M. (2019). Permissive versus restrictive temperature thresholds in critically ill children with fever and infection: A multicentre randomized clinical pilot trial. Critical Care, 23(1), https://doi.org/10.1186/s13054-019-2354-4

Background: Fever improves pathogen control at a significant metabolic cost. No randomized clinical trials (RCT) have compared fever treatment thresholds in critically ill children. We performed a pilot RCT to determine whether a definitive trial of... Read More about Permissive versus restrictive temperature thresholds in critically ill children with fever and infection: A multicentre randomized clinical pilot trial.

NUTRI-REAPED study: nutritional assessment of French critically ill children and nutrition practice survey in French-speaking pediatric intensive care units (2019)
Journal Article
Jacquot, A., Valla, F. V., Mura, T., Tume, L. N., Bertet, H., Ford-Chessel, C., …Gaillard-Le Roux, B. (2019). NUTRI-REAPED study: nutritional assessment of French critically ill children and nutrition practice survey in French-speaking pediatric intensive care units. Annals of Intensive Care, 9(1), https://doi.org/10.1186/s13613-019-0493-z

© 2019, The Author(s). Background: Impaired nutritional status is adversely associated with suboptimal outcomes in critically ill children. Undernutrition at pediatric intensive care unit (PICU) admission ranges from 15 to 65%. A lack of knowledge of... Read More about NUTRI-REAPED study: nutritional assessment of French critically ill children and nutrition practice survey in French-speaking pediatric intensive care units.