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Modelling the activation of G-protein coupled receptors by a single drug (2009)
Journal Article
Woodroffe, P. J., Bridge, L., King, J. R., & Hill, S. J. (2009). Modelling the activation of G-protein coupled receptors by a single drug. Mathematical Biosciences, 219(1), 32-55. https://doi.org/10.1016/j.mbs.2009.02.003

In this paper, the most popular proposed mechanism for activation of G-protein coupled receptors (GPCRs) - the shuttling mechanism - is modelled mathematically. An asymptotic analysis of this model clarifies the dynamics of the system in the presence... Read More about Modelling the activation of G-protein coupled receptors by a single drug.