Skip to main content

Research Repository

Advanced Search

All Outputs (14)

The role of redox mechanisms in cell signalling (2009)
Journal Article
Hancock, J. T. (2009). The role of redox mechanisms in cell signalling. Molecular Biotechnology, 43(2), 162-166. https://doi.org/10.1007/s12033-009-9189-1

Functioning and efficient cell signalling is vital for the survival of cells. Over the years various components have been identified and recognised as crucial for the transduction of signals in cells. Many of the mechanisms allow for a relatively rap... Read More about The role of redox mechanisms in cell signalling.

Bacterial Evolution by Genomic Island Transfer Occurs via DNA Transformation In Planta (2009)
Journal Article
Godfrey, S. A. C., Lovell, H. C., Mansfield, J. W., Jackson, R. W., Hancock, J. T., & Arnold, D. L. (2009). Bacterial Evolution by Genomic Island Transfer Occurs via DNA Transformation In Planta. Current Biology, 19(18), 1586-1590. https://doi.org/10.1016/j.cub.2009.08.018

Our understanding of the evolution of microbial pathogens has been advanced by the discovery of "islands" of DNA that differ from core genomes and contain determinants of virulence [1, 2]. The acquisition of genomic islands (GIs) by horizontal gene t... Read More about Bacterial Evolution by Genomic Island Transfer Occurs via DNA Transformation In Planta.

Reactive oxygen species, nitric oxide and signal crosstalk (2009)
Book Chapter
Neill, S., Hancock, J. T., & Wilson, I. D. (2009). Reactive oxygen species, nitric oxide and signal crosstalk. In K. Yoshioka, & K. Shinozaki (Eds.), Signal Crosstalk in Plant Stress Responses (136-160). Iowa: Wiley-Blackwell

The effects of glucose ingestion and glucose regulation on memory performance in older adults with mild cognitive impairment (2009)
Journal Article
Hancock, J., Riby, L., Marriott, A., Bullock, R., Hancock, J., Smallwood, J., & McLaughlin, J. (2009). The effects of glucose ingestion and glucose regulation on memory performance in older adults with mild cognitive impairment. European Journal of Clinical Nutrition, 63(4), 566-571. https://doi.org/10.1038/sj.ejcn.1602981

Background/Objectives: Previous research investigating the impact of glucose ingestion and/or improvements in glucose regulation has found selective cognitive facilitation on episodic memory tasks in successful ageing and dementia. The present study... Read More about The effects of glucose ingestion and glucose regulation on memory performance in older adults with mild cognitive impairment.

S-Nitrosoglutathione inactivation of the mitochondrial and cytosolic BCAT proteins: S-nitrosation and S-thiolation (2009)
Journal Article
Coles, S. J., Easton, P., Sharrod, H., Hutson, S. M., Hancock, J. T., Patel, V., & Conway, M. E. (2009). S-Nitrosoglutathione inactivation of the mitochondrial and cytosolic BCAT proteins: S-nitrosation and S-thiolation. Biochemistry, 48(3), 645-656. https://doi.org/10.1021/bi801805h

Specific proteins with reactive thiol(ate) groups are susceptible to nitric oxide (NO) modification, which can result in S-nitrosation, S-thiolation, or disulfide bond formation. In the present study the effect of NO modification on the functionality... Read More about S-Nitrosoglutathione inactivation of the mitochondrial and cytosolic BCAT proteins: S-nitrosation and S-thiolation.

S-nitrosoglutathione inactivation of the mitochondrial and cytosolic BCAT proteins: S-nitrosation and s-thiolation (2009)
Journal Article
Coles, S. J., Easton, P., Sharrod, H., Hutson, S. M., Hancock, J. T., Patel, V. B., & Conway, M. E. (2009). S-nitrosoglutathione inactivation of the mitochondrial and cytosolic BCAT proteins: S-nitrosation and s-thiolation. Biochemistry, 48(3), 645-656. https://doi.org/10.1021/bi801805h

Specific proteins with reactive thiol(ate) groups are susceptible to nitric oxide (NO) modification, which can result in S-nitrosation, S-thiolation, or disulfide bond formation. In the present study the effect of NO modification on the functionality... Read More about S-nitrosoglutathione inactivation of the mitochondrial and cytosolic BCAT proteins: S-nitrosation and s-thiolation.

Pollen generates nitric oxide and nitrite: a possible link to pollen-induced allergic responses (2009)
Journal Article
Bright, J., Hiscock, S. J., James, P. E., & Hancock, J. T. (2009). Pollen generates nitric oxide and nitrite: a possible link to pollen-induced allergic responses. Plant Physiology and Biochemistry, 47(1), 49-55. https://doi.org/10.1016/j.plaphy.2008.09.005

Reactive nitrogen species (RNS), such as nitric oxide (NO), are ubiquitous and diverse signalling molecules involved in a wide range of physiological and pathophysiological processes in both animals and plants. Nitrite, a metabolite of NO turnover, h... Read More about Pollen generates nitric oxide and nitrite: a possible link to pollen-induced allergic responses.

Tools to investigate reaction oxygen species-sensitive signaling proteins (2009)
Book Chapter
Desikan, R., Neill, S., Slinn, J., & Hancock, J. T. (2009). Tools to investigate reaction oxygen species-sensitive signaling proteins. In J. T. Hancock (Ed.), Redox-Mediated Signal Transduction (84-96). Humana Press. https://doi.org/10.1007/978-1-59745-129-1_7

The thiols groups of cysteine residues on proteins are attractive oxidative targets for modification by reactive oxygen species, such as hydrogen peroxide (H2O2). Such modification can lead to important cellular signaling processes that ultimately re... Read More about Tools to investigate reaction oxygen species-sensitive signaling proteins.

Cell signalling is the music of life (2009)
Journal Article
Hancock, J. T. (2009). Cell signalling is the music of life. British Journal of Biomedical Science, 65, 205-208

Cell signalling is an immensely important topic in biological and biomedical sciences, and one which has an ever-increasing literature. As more and more is known about it, and more components are discovered, it is getting harder and harder to visuali... Read More about Cell signalling is the music of life.

Lipid peroxidation levels in soybean (Glycine max (L.) Merr.) seed parts as a consequence on imbibition stress (2009)
Journal Article
Lisjak, M., Wilson, I. D., Civale, L., Hancock, J. T., & Teklic, T. (2009). Lipid peroxidation levels in soybean (Glycine max (L.) Merr.) seed parts as a consequence on imbibition stress. Agriculture, 15, 32-37

High rainfall and rapid water uptake by dry seed after sowing in the field can result in so-called seed imbibitional damage. Here, lipid peroxidation levels were evaluated in seed testa, embryos and cotyledons of three soybean cultivars (Podravka 95,... Read More about Lipid peroxidation levels in soybean (Glycine max (L.) Merr.) seed parts as a consequence on imbibition stress.

Differential requirement for NO during ABA-induced stomatal closure in turgid and wilted leaves (2009)
Journal Article
Harrison, J., Ribeiro, D. M., Desikan, R., Bright, J., Confraria, A., Hancock, J. T., …Wilson, I. D. (2009). Differential requirement for NO during ABA-induced stomatal closure in turgid and wilted leaves. Plant, Cell and Environment, 32(1), 46-57. https://doi.org/10.1111/j.1365-3040.2008.01906.x

Abscisic acid (ABA)-induced stomatal closure is mediated by a complex, guard cell signalling network involving nitric oxide (NO) as a key intermediate. However, there is a lack of information concerning the role of NO in the ABA-enhanced stomatal clo... Read More about Differential requirement for NO during ABA-induced stomatal closure in turgid and wilted leaves.

Role of nitric oxide in regulating stomatal apertures (2009)
Journal Article
Wilson, I. D., Ribeiro, D. M., Bright, J., Confraria, A., Harrison, J., Barros, R. S., …Hancock, J. T. (2009). Role of nitric oxide in regulating stomatal apertures. Plant Signaling and Behavior, 4(5), 467-469. https://doi.org/10.4161/psb.4.5.8545

During stomatal closure, nitric oxide (NO) operates as one of the key intermediates in the complex, abscisic acid (ABA)-mediated, guard cell signaling network that regulates this process. However, data concerning the role of NO in stomatal closure th... Read More about Role of nitric oxide in regulating stomatal apertures.