All Outputs (3)

Colorectal cancer progression to metastasis is associated with dynamic genome-wide biphasic 5-hydroxymethylcytosine accumulation (2025)
Journal Article

Background: Colorectal cancer (CRC) progression from adenoma to adenocarcinoma is associated with global reduction in 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC). DNA hypomethylation continues upon liver metastasis. Here we examine 5hmC... Read More about Colorectal cancer progression to metastasis is associated with dynamic genome-wide biphasic 5-hydroxymethylcytosine accumulation.

Gut bacteria promote proliferation in benign S/RG/C2 colorectal tumour cells, and promote proliferation, migration and invasion in malignant HCT116 cells (2023)
Journal Article

Colorectal cancer (CRC) is a significant global health burden with a rising incidence worldwide. Distinct bacterial populations are associated with CRC development and progression, and it is thought that the relationship between CRC and associated gu... Read More about Gut bacteria promote proliferation in benign S/RG/C2 colorectal tumour cells, and promote proliferation, migration and invasion in malignant HCT116 cells.

Investigating the disease-promoting abilities of gut bacteria in colorectal tumour cells (2021)
Thesis

Colorectal cancer (CRC) is the third most common malignancy worldwide and the second leading cause of cancer-related death. The global burden of CRC is rising, particularly in younger populations. This increase has been attributed to lifestyle factor... Read More about Investigating the disease-promoting abilities of gut bacteria in colorectal tumour cells.