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Barriers to implementing antimicrobial stewardship programmes in three Saudi hospitals: Evidence from a qualitative study (2019)
Journal Article
Alghamdi, S., Atef-Shebl, N., Aslanpour, Z., & Berrou, I. (2019). Barriers to implementing antimicrobial stewardship programmes in three Saudi hospitals: Evidence from a qualitative study. Journal of Global Antimicrobial Resistance, 18, 284-290. https://doi.org/10.1016/j.jgar.2019.01.031

© 2019 International Society for Chemotherapy of Infection and Cancer Objectives: This study explored antimicrobial stewardship programme (ASP) team members’ perspectives regarding factors influencing the adoption and implementation of these programm... Read More about Barriers to implementing antimicrobial stewardship programmes in three Saudi hospitals: Evidence from a qualitative study.

This girl can: Analysis of women’s Facebook posts (2018)
Presentation / Conference
Berrou, I., & Cumberbatch, Y. (2018, September). This girl can: Analysis of women’s Facebook posts. Poster presented at 78th FIP World Congress of Pharmacy and Pharmaceutical Sciences

Conference poster

Hospital adoption of antimicrobial stewardship programmes in Gulf Cooperation Council countries: A review of existing evidence (2018)
Journal Article
Alghamdi, S., Shebl, N. A., Aslanpour, Z., Shibl, A., & Berrou, I. (2018). Hospital adoption of antimicrobial stewardship programmes in Gulf Cooperation Council countries: A review of existing evidence. Journal of Global Antimicrobial Resistance, 15, 196-209. https://doi.org/10.1016/j.jgar.2018.07.014

© 2018 International Society for Chemotherapy of Infection and Cancer Antimicrobial resistance is increasing at an alarming rate in the Gulf Cooperation Council (GCC) owing to the overuse and misuse of antimicrobials. Novel and rare multidrug-resista... Read More about Hospital adoption of antimicrobial stewardship programmes in Gulf Cooperation Council countries: A review of existing evidence.

The role of glucocorticoid receptor phosphorylation in Mcl-1 and NOXA gene expression (2010)
Journal Article
Lynch, J. T., Rajendran, R., Xenaki, G., Berrou, I., Demonacos, C., & Krstic-Demonacos, M. (2010). The role of glucocorticoid receptor phosphorylation in Mcl-1 and NOXA gene expression. Molecular Cancer, 9(38), 1-15. https://doi.org/10.1186/1476-4598-9-38

Background: The cyclin-dependent kinase (CDK) and mitogen-activated protein kinase (MAPK) mediated phosphorylation of glucocorticoid receptor (GR) exerts opposite effects on GR transcriptional activity and affects other posttranslational modification... Read More about The role of glucocorticoid receptor phosphorylation in Mcl-1 and NOXA gene expression.

Molecular mechanisms conferring resistance/sensitivity to glucocorticoid-induced apoptosis
Book Chapter
Berrou, I., Krstic-Demonacos, M., & Demonacos, C. Molecular mechanisms conferring resistance/sensitivity to glucocorticoid-induced apoptosis. In X. Xiaoxi Qian (Ed.), Glucocorticoids - New Recognition of Our Familiar FriendIntechOpen. https://doi.org/10.5772/51467

Resistance to glucocorticoid induced apoptosis in acute lymphoblastic leukaemia (ALL) has been attributed to several different processes and pathways including predominance of certain GR isoforms with reduced transcriptional activity, either due to a... Read More about Molecular mechanisms conferring resistance/sensitivity to glucocorticoid-induced apoptosis.

ROS & energy production pathways in the determination of resistance/sensitivity to glucocorticoids-induced apoptosis in acute lymphoblastic leukaemia
Thesis
Berrou, I. ROS & energy production pathways in the determination of resistance/sensitivity to glucocorticoids-induced apoptosis in acute lymphoblastic leukaemia. (Thesis). The University of Manchester

Glucocorticoids have long been used in the treatment of acute lymphoblastic leukaemia due to their ability to cause cell cycle arrest and apoptosis of lymphoid cells. However, some patients do not respond to glucocorticoid treatment and the majority,... Read More about ROS & energy production pathways in the determination of resistance/sensitivity to glucocorticoids-induced apoptosis in acute lymphoblastic leukaemia.


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