All Outputs (2)

Atmin is a transcriptional regulator of both lung morphogenesis and ciliogenesis (2014)
Journal Article
Stevens, J. L., Goggolidou, P., L. Stevens, J., Agueci, F., Keynton, J., Wheway, G., …Norris, D. P. (2014). Atmin is a transcriptional regulator of both lung morphogenesis and ciliogenesis. Development, 141(20), 3966-3977. https://doi.org/10.1242/dev.107755

© 2014. Initially identified in DNA damage repair, ATM-interactor (ATMIN) further functions as a transcriptional regulator of lung morphogenesis. Here we analyse three mouse mutants, Atmingpg6/gpg6, AtminH210Q/H210Q and Dynll1GT/GT, revealing how ATM... Read More about Atmin is a transcriptional regulator of both lung morphogenesis and ciliogenesis.

Loss-of-function mutations in MICU1 cause a brain and muscle disorder linked to primary alterations in mitochondrial calcium signaling (2014)
Journal Article
Duchen, M. R., Sewry, C. A., Den Dunnen, J. T., Niks, E. H., Santen, G. W., Morgan, J. E., …Sheridan, E. (2014). Loss-of-function mutations in MICU1 cause a brain and muscle disorder linked to primary alterations in mitochondrial calcium signaling. Nature Genetics, 46(2), 188-193. https://doi.org/10.1038/ng.2851

Mitochondrial Ca 2+ uptake has key roles in cell life and death. Physiological Ca 2+ signaling regulates aerobic metabolism, whereas pathological Ca 2+ overload triggers cell death. Mitochondrial Ca 2+ uptake is mediated by the Ca 2+ uniporter comple... Read More about Loss-of-function mutations in MICU1 cause a brain and muscle disorder linked to primary alterations in mitochondrial calcium signaling.