All Outputs (3)

Signaling through the primary cilium (2018)
Journal Article
Wheway, G., Nazlamova, L., & Hancock, J. T. (2018). Signaling through the primary cilium. Frontiers in Cell and Developmental Biology, 6(FEB), https://doi.org/10.3389/fcell.2018.00008

© 2018 Wheway, Nazlamova and Hancock. The presence of single, non-motile "primary" cilia on the surface of epithelial cells has been well described since the 1960s. However, for decades these organelles were believed to be vestigial, with no remainin... Read More about Signaling through the primary cilium.

The role of primary cilia in the development and disease of the retina (2013)
Journal Article
Parry, D. A., Johnson, C. A., Wheway, G., Parry, D. A., & Johnson, C. A. (2014). The role of primary cilia in the development and disease of the retina. Organogenesis, 10(1), 69-85. https://doi.org/10.4161/org.26710

The normal development and function of photoreceptors is essential for eye health and visual acuity in vertebrates. Mutations in genes encoding proteins involved in photoreceptor development and function are associated with a suite of inherited retin... Read More about The role of primary cilia in the development and disease of the retina.

The SYSCILIA gold standard (SCGSv1) of known ciliary components and its applications within a systems biology consortium (2013)
Journal Article
Giles, R. H., Slaats, G. G., Van Dam, T. J., Huynen, M. A., van Dam, T. J., Wheway, G., …Giles, R. H. (2013). The SYSCILIA gold standard (SCGSv1) of known ciliary components and its applications within a systems biology consortium. Cilia, 2(1), 7. https://doi.org/10.1186/2046-2530-2-7

The multinational SYSCILIA consortium aims to gain a mechanistic understanding of the cilium. We utilize multiple parallel high-throughput (HTP) initiatives to develop predictive models of relationships between complex genotypes and variable phenotyp... Read More about The SYSCILIA gold standard (SCGSv1) of known ciliary components and its applications within a systems biology consortium.