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All Outputs (3)

Tissue inhibitor of metalloproteinase-3 differentially binds to components of Bruch's membrane (2006)
Journal Article
Dick, A. D., Majid, M. A., Smith, V. A., Matthews, F., & Newby, A. C. (2006). Tissue inhibitor of metalloproteinase-3 differentially binds to components of Bruch's membrane. British Journal of Ophthalmology, 90(10), 1310-1315. https://doi.org/10.1136/bjo.2006.097246

Background: Sorsby's fundus dystrophy (SFD) is caused by mutations in tissue inhibitor of metalloproteinase (TIMP)-3 and, with the exception of early onset, is similar to age-related macular degeneration. The pathological features of this condition r... Read More about Tissue inhibitor of metalloproteinase-3 differentially binds to components of Bruch's membrane.

Nucleolar protein upstream binding factor is sequestered into adenovirus DNA replication centres during infection without affecting RNA polymerase I location or ablating rRNA synthesis (2006)
Journal Article
Lawrence, F., McStay, B., & Matthews, D. A. (2006). Nucleolar protein upstream binding factor is sequestered into adenovirus DNA replication centres during infection without affecting RNA polymerase I location or ablating rRNA synthesis. Journal of Cell Science, 119(12), 2621-2631. https://doi.org/10.1242/%E2%80%8Bjcs.02982

When human adenovirus infects human cells there is disruption of rRNA biogenesis. This report examines the effect of adenovirus infection on the nucleolar protein, upstream binding factor (UBF) which plays a major role in regulating rRNA synthesis. W... Read More about Nucleolar protein upstream binding factor is sequestered into adenovirus DNA replication centres during infection without affecting RNA polymerase I location or ablating rRNA synthesis.

Keratoconus: Matrix metalloproteinase-2 activation and TIMP modulation (2006)
Journal Article
Majid, M. A., Smith, V. A., Matthews, F., & Cook, S. D. (2006). Keratoconus: Matrix metalloproteinase-2 activation and TIMP modulation. BBA - Molecular Basis of Disease, 1762(4), 431-439. https://doi.org/10.1016/j.bbadis.2006.01.010

Keratoconus is an ocular condition that causes corneal thinning, cone formation and scarring. In view of a hypothesis that activated MMP-2 may initiate or facilitate disease progression, the MMP-2/TIMP systems of stromal cells derived from normal and... Read More about Keratoconus: Matrix metalloproteinase-2 activation and TIMP modulation.