Performance of silica monoliths for basic compounds. Silanol activity
(2011)
Book Chapter
McCalley, D. V. (2011). Performance of silica monoliths for basic compounds. Silanol activity. In K. K. Unger, N. Tanaka, & E. Mactejevas (Eds.), Monolithic silicas in separation science (173-188). Weinheim, Germany: Wiley VCH
The large majority of pharmaceuticals, and in addition many compounds of biomedical significance, contain ionisable basic groups. This chapter considers the analysis of these important compounds on silica monolith columns.