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Evolving spiking networks with variable resistive memories (2014)
Journal Article
Gale, E., Howard, G., Howard, G. D., Bull, L., de Lacy Costello, B., & Adamatzky, A. (2014). Evolving spiking networks with variable resistive memories. Evolutionary Computation, 22(1), 79-103. https://doi.org/10.1162/EVCO_a_00103

Neuromorphic computing is a brainlike information processing paradigm that requires adaptive learning mechanisms. A spiking neuro-evolutionary system is used for this purpose; plastic resistive memories are implemented as synapses in spiking neural n... Read More about Evolving spiking networks with variable resistive memories.

Drop-coated titanium dioxide memristors (2014)
Journal Article
Gale, E., Mayne, R., Adamatzky, A., & De Lacy Costello, B. (2014). Drop-coated titanium dioxide memristors. Materials Chemistry and Physics, 143(2), 524-529. https://doi.org/10.1016/j.matchemphys.2013.09.013

The fabrication of memristors by drop-coating sol-gel Ti(OH)4 solution onto either aluminium foil or sputter-coated aluminium on plastic is presented. The gel layer is thick, 37 μm, but both devices exhibit good memristance I-V profiles. The drop coa... Read More about Drop-coated titanium dioxide memristors.

Sensory fusion in Physarum polycephalum and implementing multi-sensory functional computation (2014)
Journal Article
de Lacy Costello, B. P. J., Whiting, J. G. H., Whiting, J., de Lacy Costello, B., & Adamatzky, A. (2014). Sensory fusion in Physarum polycephalum and implementing multi-sensory functional computation. BioSystems, 119(1), 45-52. https://doi.org/10.1016/j.biosystems.2014.03.003

Surface electrical potential and observational growth recordings were made of a protoplasmic tube of the slime mould Physarum polycephalum in response to a multitude of stimuli with regards to sensory fusion or multisensory integration. Each stimulus... Read More about Sensory fusion in Physarum polycephalum and implementing multi-sensory functional computation.

A review of the volatiles from the healthy human body (2014)
Journal Article
Ratcliffe, N. M., Al-Kateb, H., De Lacy Costello, B., de Lacy Costello, B., Amann, A., Al-Kateb, H., …Ratcliffe, N. M. (2014). A review of the volatiles from the healthy human body. Journal of Breath Research, 8(1), https://doi.org/10.1088/1752-7155/8/1/014001

A compendium of all the volatile organic compounds (VOCs) emanating from the human body (the volatolome) is for the first time reported. 1840 VOCs have been assigned from breath (872), saliva (359), blood (154), milk (256), skin secretions (532) urin... Read More about A review of the volatiles from the healthy human body.

The use of a gas chromatograph coupled to a metal oxide sensor for rapid assessment of stool samples from irritable bowel syndrome and inflammatory bowel disease patients (2014)
Journal Article
Ratcliffe, N. M., Probert, C. S., Vaughan, K., De Lacy Costello, B. P., McGuire, N. D., Shepherd, S. F., …Ratcliffe, N. M. (2014). The use of a gas chromatograph coupled to a metal oxide sensor for rapid assessment of stool samples from irritable bowel syndrome and inflammatory bowel disease patients. Journal of Breath Research, 8(2), https://doi.org/10.1088/1752-7155/8/2/026001

There is much clinical interest in the development of a low-cost and reliable test for diagnosing inflammatory bowel disease (IBD) and irritable bowel syndrome (IBS), two very distinct diseases that can present with similar symptoms. The assessment o... Read More about The use of a gas chromatograph coupled to a metal oxide sensor for rapid assessment of stool samples from irritable bowel syndrome and inflammatory bowel disease patients.

Emergent spiking in non-ideal memristor networks (2014)
Journal Article
Costello, B. D. L., Gale, E., de Lacy Costello, B., & Adamatzky, A. (2014). Emergent spiking in non-ideal memristor networks. Microelectronics Journal, 45(11), 1401-1415. https://doi.org/10.1016/j.mejo.2014.06.008

© 2014 Elsevier Ltd. All rights reserved. Memristors have uses as artificial synapses and perform well in this role in simulations with artificial spiking neurons. Our experiments show that memristor networks natively spike and can exhibit emergent o... Read More about Emergent spiking in non-ideal memristor networks.

Towards point of care testing for C. difficile infection by volatile profiling, using the combination of a short multi-capillary gas chromatography column with metal oxide sensor detection (2014)
Journal Article
Ratcliffe, N. M., Vaughan, K., Probert, C. S., Garner, C. E., De Lacy Costello, B., McGuire, N. D., …Ratcliffe, N. M. (2014). Towards point of care testing for C. difficile infection by volatile profiling, using the combination of a short multi-capillary gas chromatography column with metal oxide sensor detection. Measurement Science and Technology, 25(6), https://doi.org/10.1088/0957-0233/25/6/065108

Rapid volatile profiling of stool sample headspace was achieved using a combination of short multi-capillary chromatography column (SMCC), highly sensitive heated metal oxide semiconductor sensor and artificial neural network software. For direct ana... Read More about Towards point of care testing for C. difficile infection by volatile profiling, using the combination of a short multi-capillary gas chromatography column with metal oxide sensor detection.

Slime mould logic gates based on frequency changes of electrical potential oscillation (2014)
Journal Article
de Lacy Costello, B. P. J., Whiting, J. G. H., Whiting, J., de Lacy Costello, B., & Adamatzky, A. (2014). Slime mould logic gates based on frequency changes of electrical potential oscillation. BioSystems, 124, 21-25. https://doi.org/10.1016/j.biosystems.2014.08.001

Physarum polycephalum is a large single amoeba cell, which in its plasmodial phase, forages and connects nearby food sources with protoplasmic tubes. The organism forages for food by growing these tubes towards detected foodstuff, this foraging behav... Read More about Slime mould logic gates based on frequency changes of electrical potential oscillation.

Towards slime mould chemical sensor: Mapping chemical inputs onto electrical potential dynamics of Physarum Polycephalum (2013)
Journal Article
De Lacy Costello, B. P., Whiting, J. G., Whiting, J., de Lacy Costello, B., & Adamatzky, A. (2014). Towards slime mould chemical sensor: Mapping chemical inputs onto electrical potential dynamics of Physarum Polycephalum. Sensors and Actuators B: Chemical, 191, 844-853. https://doi.org/10.1016/j.snb.2013.10.064

Plasmodium of slime mould Physarum polycephalum is a large single celled organism visible unaided by the eye. This slime mould is capable of optimising the shape of its protoplasmic networks in spatial configurations of attractants and repellents. Su... Read More about Towards slime mould chemical sensor: Mapping chemical inputs onto electrical potential dynamics of Physarum Polycephalum.

Breath volatile analysis from patients diagnosed with harmful drinking, cirrhosis and hepatic encephalopathy: A pilot study (2013)
Journal Article
Ratcliffe, N. M., Costello, B. D. L., Khalid, T. Y., de Lacy Costello, B., Ewen, R., White, P., …Probert, C. S. (2013). Breath volatile analysis from patients diagnosed with harmful drinking, cirrhosis and hepatic encephalopathy: A pilot study. Metabolomics, 9(5), 938-948. https://doi.org/10.1007/s11306-013-0510-4

Hepatic encephalopathy (HE) is a neuropsychiatric state potentially complicating cirrhosis following the accumulation of toxic compounds that cross the blood-brain barrier and affect brain function; the compounds may undergo alveolar gas exchange and... Read More about Breath volatile analysis from patients diagnosed with harmful drinking, cirrhosis and hepatic encephalopathy: A pilot study.

An investigation of volatile organic compounds from the saliva of healthy individuals using headspace-trap/GC-MS (2013)
Journal Article
Ratcliffe, N., De Lacy Costello, B., Al-Kateb, H., de Lacy Costello, B., & Ratcliffe, N. M. (2013). An investigation of volatile organic compounds from the saliva of healthy individuals using headspace-trap/GC-MS. Journal of Breath Research, 7(3), https://doi.org/10.1088/1752-7155/7/3/036004

Analysis of volatile organic compounds (VOCs) from saliva, to aid disease diagnoses, has received little attention. This work aims to address the paucity of information on saliva volatiles and includes a database of newly identified compounds whilst... Read More about An investigation of volatile organic compounds from the saliva of healthy individuals using headspace-trap/GC-MS.

The Development of Novel Fuel Dehydrating Icing Inhibitors (2013)
Journal Article
Lam, J. K., de Lacy Costello, B., Repetto, S. L., Repetto, S., Costello, J. F., de Lacy Costello, B., …Lam, J. (2013). The Development of Novel Fuel Dehydrating Icing Inhibitors. SAE International Journal of Fuels and Lubricants, 6(3), 553-563. https://doi.org/10.4271/2013-01-2169

Dissolved water is a normal component of jet fuel which is vapourised during combustion; however, free water is a contaminant that can starve engines, freeze to form ice crystals capable of blocking fuel feeds, support microbial growth, and contribut... Read More about The Development of Novel Fuel Dehydrating Icing Inhibitors.

Analysis of the volatiles in the headspace above the plasmodium and sporangia of the slime mould (Physarum polycephalum) by SPME-GCMS (2013)
Journal Article
AL-Kateb, H., & Costello, B. D. L. (2013). Analysis of the volatiles in the headspace above the plasmodium and sporangia of the slime mould (Physarum polycephalum) by SPME-GCMS

Solid phase micro-extraction (SPME) coupled with Gas Chromatography Mass Spectrometry (GC-MS) was used to extract and analyse the volatiles in the headspace above the plasmodial and sporulating stages of the slime mould Physarum Polycephalum. In tota... Read More about Analysis of the volatiles in the headspace above the plasmodium and sporangia of the slime mould (Physarum polycephalum) by SPME-GCMS.

A Pilot Study Combining a GC-Sensor Device with a Statistical Model for the Identification of Bladder Cancer from Urine Headspace (2013)
Journal Article
Ratcliffe, N., Probert, C. S., Ewen, R., Khalid, T., White, P., De Lacy Costello, B., …Ratcliffe, N. M. (2013). A Pilot Study Combining a GC-Sensor Device with a Statistical Model for the Identification of Bladder Cancer from Urine Headspace. PLoS ONE, 8(7), https://doi.org/10.1371/journal.pone.0069602

There is a need to reduce the number of cystoscopies on patients with haematuria. Presently there are no reliable biomarkers to screen for bladder cancer. In this paper, we evaluate a new simple in-house fabricated, GC-sensor device in the diagnosis... Read More about A Pilot Study Combining a GC-Sensor Device with a Statistical Model for the Identification of Bladder Cancer from Urine Headspace.

Observation, characterization and modeling of memristor current spikes (2013)
Journal Article
Gale, E., de Lacy Costello, B., & Adamatzky, A. (2013). Observation, characterization and modeling of memristor current spikes. https://doi.org/10.12785/amis/070418

Memristors have been compared to neurons (usually specifically the synapses) since 1976 but no experimental evidence has been offered for support for this position. Here we highlight that memristors naturally form fast-response, highly reproducible a... Read More about Observation, characterization and modeling of memristor current spikes.

The importance of methane breath testing: A review (2013)
Journal Article
Ratcliffe, N. M., De Lacy Costello, B. P., de Lacy Costello, B., Ledochowski, M., & Ratcliffe, N. M. (2013). The importance of methane breath testing: A review. Journal of Breath Research, 7(2), https://doi.org/10.1088/1752-7155/7/2/024001

Sugar malabsorption in the bowel can lead to bloating, cramps, diarrhea and other symptoms of irritable bowel syndrome as well as affecting absorption of other nutrients. The hydrogen breath test is now a well established noninvasive test for assessi... Read More about The importance of methane breath testing: A review.

The use of MS for the investigation of irritable bowel syndrome and inflammatory bowel disease (2013)
Journal Article
Ratcliffe, N. M., de Lacy Costello, B., & Shepherd, S. (2013). The use of MS for the investigation of irritable bowel syndrome and inflammatory bowel disease. Clinical laboratory international, 37, 18-20

Currently, the diagnosis of bowel diseases such as irritable bowel syndrome (IBS) and inflammatory bowel disease (IBD) relies on invasive and expensive procedures. Identification of biomarker-based tests to aid diagnosis is an important area of resea... Read More about The use of MS for the investigation of irritable bowel syndrome and inflammatory bowel disease.

Design of a hybrid robot control system using memristor-model and ant-inspired based information transfer protocols (2013)
Presentation / Conference
Gale, E., de Lacy Costello, B., & Adamatzky, A. (2013, May). Design of a hybrid robot control system using memristor-model and ant-inspired based information transfer protocols. Paper presented at Workshop on Unconventional Approaches to Robotics, Automation and Control Inspired by Nature

It is not always possible for a robot to process all the information from its sensors in a timely manner and thus quick and yet valid approximations of the robot's situation are needed. Here we design hybrid control for a robot within this limit usin... Read More about Design of a hybrid robot control system using memristor-model and ant-inspired based information transfer protocols.

Does the D.C. response of memristors allow robotic short-term memory and a possible route to artificial time perception? (2013)
Presentation / Conference
Gale, E., de Lacy Costello, B., & Adamatzky, A. (2013, May). Does the D.C. response of memristors allow robotic short-term memory and a possible route to artificial time perception?. Paper presented at Workshop Unconventional Approaches to Robotics, Automation and Control Inspired by Nature (UARACIN) in:

Time perception is essential for task switching, and in the mammalian brain appears alongside other processes. Memristors are electronic components used as synapses and as models for neurons. The d.c. response of memristors can be considered as a typ... Read More about Does the D.C. response of memristors allow robotic short-term memory and a possible route to artificial time perception?.

Volatile organic compounds (VOCs) found in urine and stool (2013)
Book Chapter
de Lacy Costello, B., & Ratcliffe, N. M. (2013). Volatile organic compounds (VOCs) found in urine and stool. In A. Amann, & D. Smith (Eds.), Volatile Biomarkers: Non-Invasive Diagnosis in Physiology and Medicine, 405-462. Elsevier