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All Outputs (63)

Urinary Volatile Organic Compound Testing in Fast-Track Patients with Suspected Colorectal Cancer (2022)
Journal Article
Boulind, C. E., Gould, O., Costello, B. D. L., Allison, J., White, P., Ewings, P., …Francis, N. K. (2022). Urinary Volatile Organic Compound Testing in Fast-Track Patients with Suspected Colorectal Cancer. Cancers, 14(9), 2127. https://doi.org/10.3390/cancers14092127

Colorectal symptoms are common but only infrequently represent serious pathology, including colorectal cancer (CRC). A large number of invasive tests are presently performed for reassurance. We investigated the feasibility of urinary volatile organic... Read More about Urinary Volatile Organic Compound Testing in Fast-Track Patients with Suspected Colorectal Cancer.

Application of a solid-phase microextraction-gas chromatography-mass spectrometry/metal oxide sensor system for detection of antibiotic susceptibility in urinary tract infection-causing Escherichia coli – A proof of principle study (2021)
Journal Article
Drabińska, N., Hewett, K., White, P., Avison, M., Persad, R., Ratcliffe, N., & de Lacy Costello, B. (2021). Application of a solid-phase microextraction-gas chromatography-mass spectrometry/metal oxide sensor system for detection of antibiotic susceptibility in urinary tract infection-causing Escherichia coli – A proof of principle study. Advances in Medical Sciences, 67(1), 1-9. https://doi.org/10.1016/j.advms.2021.09.001

Purpose: Antibiotic resistance is widespread throughout the world and represents a serious health concern. There is an urgent need for the development of novel tools for rapidly distinguishing antibiotic resistant bacteria from susceptible strains. P... Read More about Application of a solid-phase microextraction-gas chromatography-mass spectrometry/metal oxide sensor system for detection of antibiotic susceptibility in urinary tract infection-causing Escherichia coli – A proof of principle study.

Towards the identification of antibiotic-resistant bacteria causing urinary tract infections using volatile organic compounds analysis—a pilot study (2020)
Journal Article
Hewett, K., Drabinska, N., White, P., Avison, M., Persad, R., Ratcliffe, N., & de Lacy Costello, B. (2020). Towards the identification of antibiotic-resistant bacteria causing urinary tract infections using volatile organic compounds analysis—a pilot study. Antibiotics, 9(11), 797. https://doi.org/10.3390/antibiotics9110797

Antibiotic resistance is an unprecedented threat to modern medicine. The analysis of volatile organic compounds (VOCs) from bacteria potentially offers a rapid way to determine antibiotic susceptibility in bacteria. This study aimed to find the optim... Read More about Towards the identification of antibiotic-resistant bacteria causing urinary tract infections using volatile organic compounds analysis—a pilot study.

Contactless sensing of liquid marbles for detection, characterisation & computing (2019)
Journal Article
Draper, T. C., Phillips, N., Weerasekera, R., Mayne, R., Fullarton, C., de Lacy Costello, B., & Adamatzky, A. (2020). Contactless sensing of liquid marbles for detection, characterisation & computing. Lab on a Chip, 20(1), 136-146. https://doi.org/10.1039/c9lc01001g

Liquid marbles (LMs) are of growing interest in many fields, including microfluidics, microreactors, sensors, and signal carriers. The generation of LMs is generally performed manually, although there has recently been a burst of publications involvi... Read More about Contactless sensing of liquid marbles for detection, characterisation & computing.

Neuromorphic liquid marbles with aqueous carbon nanotube cores (2019)
Journal Article
Mayne, R., Draper, T. C., Phillips, N., Whiting, J. G. H., Weerasekera, R., Fullarton, C., …Adamatzky, A. (2019). Neuromorphic liquid marbles with aqueous carbon nanotube cores. Langmuir, 35, 13182-13188. https://doi.org/10.1021/acs.langmuir.9b02552

Neuromorphic computing devices attempt to emulate features of biological nervous systems through mimicking the properties of synapses, towards implementing the emergent properties of their counterparts, such as learning. Inspired by recent advances i... Read More about Neuromorphic liquid marbles with aqueous carbon nanotube cores.

Mapping outcomes of liquid marble collisions (2019)
Journal Article
Draper, T. C., Fullarton, C., Mayne, R., Phillips, N., Canciani, G. E., De Lacy Costello, B. P., & Adamatzky, A. (2019). Mapping outcomes of liquid marble collisions. Soft Matter, 15(17), 3541-3551. https://doi.org/10.1039/c9sm00328b

© 2019 The Royal Society of Chemistry. Liquid marbles (LMs) have many promising roles in the ongoing development of microfluidics, microreactors, bioreactors, and unconventional computing. In many of these applications, the coalescence of two LMs is... Read More about Mapping outcomes of liquid marble collisions.

Thermal switch of oscillation frequency in belousov- zhabotinsky liquid marbles (2019)
Journal Article
Adamatzky, A., Fullarton, C., Phillips, N., Costello, B. D. L., & Draper, T. C. (2019). Thermal switch of oscillation frequency in belousov- zhabotinsky liquid marbles. Royal Society Open Science, 6(4), 190078. https://doi.org/10.1098/rsos.190078

© 2019 The Authors. External control of oscillation dynamics in the Belousov- Zhabotinsky (BZ) reaction is important for many applications including encoding computing schemes. When considering the BZ reaction, there are limited studies dealing with... Read More about Thermal switch of oscillation frequency in belousov- zhabotinsky liquid marbles.

Liquid Marble Actuator for Microfluidic Logic Systems (2018)
Journal Article
Draper, T. C., Fullarton, C., Phillips, N., de Lacy Costello, B. P. J., & Adamatzky, A. (2018). Liquid Marble Actuator for Microfluidic Logic Systems. Scientific Reports, 8(1), https://doi.org/10.1038/s41598-018-32540-w

© 2018, The Author(s). A mechanical flip-flop actuator has been developed that allows for the facile re-routing and distribution of liquid marbles (LMs) in digital microfluidic devices. Shaped loosely like a triangle, the actuating switch pivots fro... Read More about Liquid Marble Actuator for Microfluidic Logic Systems.

Belousov-Zhabotinsky reaction in liquid marbles (2018)
Journal Article
Fullarton, C., Draper, T., Phillips, N., de Lacy Costello, B., & Adamatzky, A. (2019). Belousov-Zhabotinsky reaction in liquid marbles. Journal of Physics: Materials, 2(1), https://doi.org/10.1088/2515-7639/aaed4c

In Belousov–Zhabotinsky (BZ) type reactions, chemical oxidation waves can be exploited to produce reaction-diffusion processors. This paper reports on a new method of encapsulating BZ solution in a powder coating of either polyethylene (PE) or polyte... Read More about Belousov-Zhabotinsky reaction in liquid marbles.

Evaporation, lifetime, and robustness studies of liquid marbles for collision-based computing (2018)
Journal Article
Fullarton, C., Draper, T., Phillips, N., Mayne, R., de Lacy Costello, B., & Adamatzky, A. (2018). Evaporation, lifetime, and robustness studies of liquid marbles for collision-based computing. Langmuir, 34(7), 2573-2580. https://doi.org/10.1021/acs.langmuir.7b04196

© 2018 American Chemical Society. Liquid marbles (LMs) have recently attracted interest for use as cargo carriers in digital microfluidics and have successfully been implemented as signal carriers in collision-based unconventional computing circuits.... Read More about Evaporation, lifetime, and robustness studies of liquid marbles for collision-based computing.

Mechanical sequential counting with liquid marbles (2018)
Journal Article
Draper, T., Fullarton, C., Phillips, N., de Lacy Costello, B., & Adamatzky, A. (2018). Mechanical sequential counting with liquid marbles. Lecture Notes in Artificial Intelligence, 10867 LNCS, 59-71. https://doi.org/10.1007/978-3-319-92435-9_5

© 2018, Springer International Publishing AG, part of Springer Nature. Here we demonstrate the first working example of a liquid marble-operated sequential binary counting device. We have designed a lightweight gate that can be actuated by the low ma... Read More about Mechanical sequential counting with liquid marbles.

Liquid marble interaction gate for collision-based computing (2017)
Journal Article
Draper, T., Fullarton, C., Phillips, N., de Lacy Costello, B., & Adamatzky, A. (2017). Liquid marble interaction gate for collision-based computing. Materials Today, 20(10), 561-568. https://doi.org/10.1016/j.mattod.2017.09.004

© 2017 Elsevier Ltd Liquid marbles are microliter droplets of liquid, encapsulated by self-organized hydrophobic particles at the liquid/air interface. They offer an efficient approach for manipulating liquid droplets and compartmentalizing reactions... Read More about Liquid marble interaction gate for collision-based computing.

Practical circuits with Physarum Wires (2016)
Journal Article
Whiting, J. G. H., Mayne, R., Moody, N., de Lacy Costello, B., & Adamatzky, A. (2016). Practical circuits with Physarum Wires. Biomedical Engineering Letters, 6(2), 57-65. https://doi.org/10.1007/s13534-016-0212-8

© 2016, Korean Society of Medical and Biological Engineering and Springer. Purpose: Protoplasmic tubes of Physarum polycephalum, also know as Physarum Wires (PW), have been previously suggested as novel bio-electronic components. Until recently, prac... Read More about Practical circuits with Physarum Wires.

Evolving unipolar memristor spiking neural networks (2015)
Journal Article
Howard, G. D., Bull, L., & De Lacy Costello, B. (2015). Evolving unipolar memristor spiking neural networks. Connection Science, 27(4), 397-416. https://doi.org/10.1080/09540091.2015.1080225

© 2015 Taylor & Francis. Neuromorphic computing – brain-like computing in hardware – typically requires myriad complimentary metal oxide semiconductor spiking neurons interconnected by a dense mesh of nanoscale plastic synapses. Memristors are freq... Read More about Evolving unipolar memristor spiking neural networks.

The effect of changing electrode metal on solution-processed flexible titanium dioxide memristors (2015)
Journal Article
Gale, E., Pearson, D., Kitson, S., Adamatzky, A., & De Lacy Costello, B. (2015). The effect of changing electrode metal on solution-processed flexible titanium dioxide memristors. Materials Chemistry and Physics, 162, 20-30. https://doi.org/10.1016/j.matchemphys.2015.03.037

© 2015 Elsevier B.V. Abstract Flexible solution-processed memristors show different behaviour dependent on the choice of electrode material. Use of gold for both electrodes leads to switchable WORM (Write Once Read Many times) resistive devices. Use... Read More about The effect of changing electrode metal on solution-processed flexible titanium dioxide memristors.

Slime mould memristors (2015)
Journal Article
Gale, E., Adamatzky, A., & de Lacy Costello, B. (2015). Slime mould memristors. BioNanoScience, 5(1), 1-8

In laboratory experiments we demonstrate that protoplasmic tubes of acellular slime mould \emph{Physarum polycephalum} show current versus voltage profiles consistent with memristive systems and that the effect is due to the living protoplasm of the... Read More about Slime mould memristors.

Transfer function of protoplasmic tubes of Physarum polycephalum (2015)
Journal Article
de Lacy Costello, B. P., Whiting, J. G. H., de Lacy Costello, B., & Adamatzky, A. (2015). Transfer function of protoplasmic tubes of Physarum polycephalum. BioSystems, 128, 48-51. https://doi.org/10.1016/j.biosystems.2015.01.009

© 2015. The slime mould Physarum polycephalum is a large single celled myxomycete; its plasmodium consists of tubes which extend to find sources of food. It has been previously shown that the tubes are conductive with a resistance of approximately 3.... Read More about Transfer function of protoplasmic tubes of Physarum polycephalum.

Evolving spiking networks with variable resistive memories (2014)
Journal Article
Howard, G., Bull, L., de Lacy Costello, B., Gale, E., & Adamatzky, A. (2014). Evolving spiking networks with variable resistive memories. Evolutionary Computation, 22(1), 79-103. https://doi.org/10.1162/EVCO_a_00103

Neuromorphic computing is a brainlike information processing paradigm that requires adaptive learning mechanisms. A spiking neuro-evolutionary system is used for this purpose; plastic resistive memories are implemented as synapses in spiking neural n... Read More about Evolving spiking networks with variable resistive memories.

Sensory fusion in Physarum polycephalum and implementing multi-sensory functional computation (2014)
Journal Article
Whiting, J., de Lacy Costello, B., & Adamatzky, A. (2014). Sensory fusion in Physarum polycephalum and implementing multi-sensory functional computation. BioSystems, 119(1), 45-52. https://doi.org/10.1016/j.biosystems.2014.03.003

Surface electrical potential and observational growth recordings were made of a protoplasmic tube of the slime mould Physarum polycephalum in response to a multitude of stimuli with regards to sensory fusion or multisensory integration. Each stimulus... Read More about Sensory fusion in Physarum polycephalum and implementing multi-sensory functional computation.

Emergent spiking in non-ideal memristor networks (2014)
Journal Article
Costello, B. D. L., Gale, E., de Lacy Costello, B., & Adamatzky, A. (2014). Emergent spiking in non-ideal memristor networks. Microelectronics Journal, 45(11), 1401-1415. https://doi.org/10.1016/j.mejo.2014.06.008

© 2014 Elsevier Ltd. All rights reserved. Memristors have uses as artificial synapses and perform well in this role in simulations with artificial spiking neurons. Our experiments show that memristor networks natively spike and can exhibit emergent o... Read More about Emergent spiking in non-ideal memristor networks.