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All Outputs (91)

Observation, characterization and modeling of memristor current spikes (2013)
Journal Article
Gale, E., de Lacy Costello, B., & Adamatzky, A. (2013). Observation, characterization and modeling of memristor current spikes. https://doi.org/10.12785/amis/070418

Memristors have been compared to neurons (usually specifically the synapses) since 1976 but no experimental evidence has been offered for support for this position. Here we highlight that memristors naturally form fast-response, highly reproducible a... Read More about Observation, characterization and modeling of memristor current spikes.

The use of MS for the investigation of irritable bowel syndrome and inflammatory bowel disease (2013)
Journal Article
Ratcliffe, N. M., de Lacy Costello, B., & Shepherd, S. (2013). The use of MS for the investigation of irritable bowel syndrome and inflammatory bowel disease. Clinical laboratory international, 37, 18-20

Currently, the diagnosis of bowel diseases such as irritable bowel syndrome (IBS) and inflammatory bowel disease (IBD) relies on invasive and expensive procedures. Identification of biomarker-based tests to aid diagnosis is an important area of resea... Read More about The use of MS for the investigation of irritable bowel syndrome and inflammatory bowel disease.

The importance of methane breath testing: A review (2013)
Journal Article
Ratcliffe, N. M., De Lacy Costello, B. P., de Lacy Costello, B., Ledochowski, M., & Ratcliffe, N. M. (2013). The importance of methane breath testing: A review. Journal of Breath Research, 7(2), https://doi.org/10.1088/1752-7155/7/2/024001

Sugar malabsorption in the bowel can lead to bloating, cramps, diarrhea and other symptoms of irritable bowel syndrome as well as affecting absorption of other nutrients. The hydrogen breath test is now a well established noninvasive test for assessi... Read More about The importance of methane breath testing: A review.

Volatile organic compounds (VOCs) found in urine and stool (2013)
Book Chapter
de Lacy Costello, B., & Ratcliffe, N. M. (2013). Volatile organic compounds (VOCs) found in urine and stool. In A. Amann, & D. Smith (Eds.), Volatile Biomarkers: Non-Invasive Diagnosis in Physiology and Medicine (405-462). Elsevier

Beyond Markov chains, towards adaptive memristor network-based music generation (2013)
Presentation / Conference
Gale, E., Matthews, O., de Lacy Costello, B., & Adamatzky, A. (2013, April). Beyond Markov chains, towards adaptive memristor network-based music generation. Paper presented at First AISB symposium on Music and Unconventional Computing, University of Exeter, UK

We undertook a study of the use of a memristor network for music generation, making use of the memristor's memory to go beyond the Markov hypothesis. Seed transition matrices are created and populated using memristor equations, and which are shown to... Read More about Beyond Markov chains, towards adaptive memristor network-based music generation.

An Investigation of Fecal Volatile Organic Metabolites in Irritable Bowel Syndrome (2013)
Journal Article
Probert, C. S., de Costello, B. L., Ahmed, I., Greenwood, R., de Lacy Costello, B., Ratcliffe, N. M., & Probert, C. (2013). An Investigation of Fecal Volatile Organic Metabolites in Irritable Bowel Syndrome. PLoS ONE, 8(3), https://doi.org/10.1371/journal.pone.0058204

Diagnosing irritable bowel syndrome (IBS) can be a challenge; many clinicians resort to invasive investigations in order to rule out other diseases and reassure their patients. Volatile organic metabolites (VOMs) are emitted from feces; understanding... Read More about An Investigation of Fecal Volatile Organic Metabolites in Irritable Bowel Syndrome.

Volatiles from oral anaerobes confounding breath biomarker discovery (2013)
Journal Article
De Lacy Costello, B., Khalid, T. Y., Ratcliffe, N. M., Khalid, T., Saad, S., Greenman, J., …Ratcliffe, N. M. (2013). Volatiles from oral anaerobes confounding breath biomarker discovery. Journal of Breath Research, 7(1), https://doi.org/10.1088/1752-7155/7/1/017114

The levels of compounds in exhaled mouth air do not necessarily reflect levels in the systemic circulation as bacteria can bio-transform substrates to produce compounds within the mouth. This should be of concern to researchers measuring breath volat... Read More about Volatiles from oral anaerobes confounding breath biomarker discovery.

A diagnostic apparatus for analysing a sample to diagnose disease (2012)
Patent
Ratcliffe, N. M., de Lacy Costello, B., Ewen, R., & Probert, C. (2012). A diagnostic apparatus for analysing a sample to diagnose disease. EP2502065 A2 (text from WO2011061308A2)

A diagnostic apparatus (10) for analysing a sample to diagnose disease, the apparatus (10) comprising: a separating element (16) for separating gas derived from the sample into component parts; a sensor arrangement (18) coupled to the separating elem... Read More about A diagnostic apparatus for analysing a sample to diagnose disease.

Logical and arithmetic circuits in Belousov-Zhabotinsky encapsulated disks (2011)
Journal Article
Holley, J., Jahan, I., De Lacy Costello, B., Bull, L., & Adamatzky, A. (2011). Logical and arithmetic circuits in Belousov-Zhabotinsky encapsulated disks. Physical Review E, 84(5), 056110. https://doi.org/10.1103/PhysRevE.84.056110

Excitation waves on a subexcitable Belousov-Zhabotinsky (BZ) substrate can be manipulated by chemical variations in the substrate and by interactions with other waves. Symbolic assignment and interpretation of wave dynamics can be used to perform log... Read More about Logical and arithmetic circuits in Belousov-Zhabotinsky encapsulated disks.

Neuromorphic computing with memristors: Preliminary experimental results (2011)
Presentation / Conference
Gale, E., de Lacy Costello, B., & Adamatzky, A. (2011, November). Neuromorphic computing with memristors: Preliminary experimental results. Poster presented at Building Bridges to Build Brains, Edinburgh

Individual memristors have been observed demonstrating neuron-like spiking patterns. It has been shown elsewhere that memristors provide superior modelling for neurons then the Hodgkin-Huxley model. Due to these results we expect memristors to be e... Read More about Neuromorphic computing with memristors: Preliminary experimental results.

A diagnostic apparatus for analysing a sample to diagnose disease (2011)
Patent
Ratcliffe, N. M., de Lacy Costello, B., Ewen, R., & Probert, C. (2011). A diagnostic apparatus for analysing a sample to diagnose disease. WO/2011/061308

A diagnostic apparatus (10) for analysing a sample to diagnose disease, the apparatus (10) comprising: a separating element (16) for separating gas derived from the sample into component parts; a sensor arrangement (18) coupled to the separating elem... Read More about A diagnostic apparatus for analysing a sample to diagnose disease.

Towards constructing one-bit binary adder in excitable chemical medium (2011)
Journal Article
de Lacy Costello, B., Adamatzky, A., Jahan, I., & Zhang, L. (2011). Towards constructing one-bit binary adder in excitable chemical medium. Chemical Physics, 381(1-3), 88-99. https://doi.org/10.1016/j.chemphys.2011.01.014

The light-sensitive modification (ruthenium catalysed) of the Belousov-Zhabotinsky reaction exhibits various excitability regimes depending on the level of illumination. Within a narrow range of applied illumination levels the medium is in a sub-exci... Read More about Towards constructing one-bit binary adder in excitable chemical medium.

Investigation of the semiochemicals of confused flour beetle Tribolium confusum Jaquelin du Val and grain weevil Sitophilus granarius (L.) in stored wheat grain and flour (2010)
Presentation / Conference
Abuelnnor, N., Jones, P., Ratcliffe, N. M., de Lacy Costello, B., & Spencer-Phillips, P. T. (2010, June). Investigation of the semiochemicals of confused flour beetle Tribolium confusum Jaquelin du Val and grain weevil Sitophilus granarius (L.) in stored wheat grain and flour. Paper presented at 10th International Working Conference on Stored Product Protection, Estoril Congress Center, Portugal

This investigation sets out to identify specific volatile compounds from both flour infested with the confused flour beetle, Tribolium confusum and wheat grain infested with the grain weevil, Sitophilus granarius. These volatiles could help to aid th... Read More about Investigation of the semiochemicals of confused flour beetle Tribolium confusum Jaquelin du Val and grain weevil Sitophilus granarius (L.) in stored wheat grain and flour.

Gas sensor (2010)
Patent
Ratcliffe, N. M., de Lacy Costello, B., & Richards, W. (2010). Gas sensor. EP20080804338

A method of detection of a volatile compound in a gaseous atmosphere comprises irradiating a semiconducting metal oxide material with ultraviolet light, exposing the irradiated material to the gaseous atmosphere and determining the presence of any vo... Read More about Gas sensor.

Chemical tessellations - Results of binary and tertiary reactions between metal ions and ferricyanide or ferrocyanide loaded gels (2010)
Journal Article
de Lacy Costello, B., Jahan, I., Hambidge, P., Locking, K., Patel, D., & Adamatzky, A. (2010). Chemical tessellations - Results of binary and tertiary reactions between metal ions and ferricyanide or ferrocyanide loaded gels. International Journal of Bifurcation and Chaos, 20(7), 2241-2252. https://doi.org/10.1142/S0218127410027064

In our recent letter [de Lacy Costello et al., 2009] we described the formation of spontaneous complex tessellations of the plane constructed in simple chemical reactions between drops of metal salts and ferricyanide or ferrocyanide loaded gels. In t... Read More about Chemical tessellations - Results of binary and tertiary reactions between metal ions and ferricyanide or ferrocyanide loaded gels.

Reaction-diffusion controllers for robots (2009)
Book Chapter
Adamatzky, A., de Lacy Costello, B., & Yokoi, H. (2009). Reaction-diffusion controllers for robots. In A. Adamatzky, & M. Komosinski (Eds.), Artificial Life Models in Hardware (233-264). London: Springer Verlag. https://doi.org/10.1007/978-1-84882-530-7_11

Excitable systems, particularly spatially extended media, exhibit a wide variety of travelling patterns and different modes of interaction. The Belousov-Zhabo-tinsky [1] (BZ) reaction is the most well known and extensively studied example of non-line... Read More about Reaction-diffusion controllers for robots.

Analysis of faecal volatile organic compounds in preterm infants who develop necrotising enterocolitis: A pilot study (2009)
Journal Article
Garner, C. E., Ewer, A. K., Elasouad, K., Power, F., Greenwood, R., Ratcliffe, N. M., …Probert, C. S. (2009). Analysis of faecal volatile organic compounds in preterm infants who develop necrotising enterocolitis: A pilot study. Journal of Pediatric Gastroenterology and Nutrition, 49(5), 559-565. https://doi.org/10.1097/MPG.0b013e3181a3bfbc

OBJECTIVE:: To determine differences in the profiles of volatile organic compounds (VOCs) in faecal samples from preterm infants who develop necrotising enterocolitis (NEC) compared with non-NEC controls. MATERIALS AND METHODS:: Daily faecal samples... Read More about Analysis of faecal volatile organic compounds in preterm infants who develop necrotising enterocolitis: A pilot study.

Experimental validation of binary collisions between wave fragments in the photosensitive Belousov–Zhabotinsky reaction (2009)
Journal Article
Toth, R., Stone, C., Adamatzky, A., de Lacy Costello, B., & Bull, L. (2009). Experimental validation of binary collisions between wave fragments in the photosensitive Belousov–Zhabotinsky reaction. Chaos, Solitons and Fractals, 41(4), 1605-1615. https://doi.org/10.1016/j.chaos.2008.07.001

Using the examples of an excitable chemical system (the Belousov–Zhabotinsky medium) and plasmodium of Physarum polycephalum we show that universal computation in a geometrically unconstrained medium is only possible when resources (excitability or c... Read More about Experimental validation of binary collisions between wave fragments in the photosensitive Belousov–Zhabotinsky reaction.

Volatiles from oral anaerobes (2009)
Presentation / Conference
Khalid, T., Ratcliffe, N. M., de Lacy Costello, B., Greenman, J., & Saad, S. (2009, April). Volatiles from oral anaerobes. Paper presented at BREATH 2009 International Conference on Breath and Breath Odor Research, Dortmund Germany