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A validation of the 7.5% CO2 model of GAD using paroxetine and lorazepam in healthy volunteers (2007)
Journal Article
Bailey, J. E., Kendrick, A., Diaper, A., Potokar, J. P., & Nutt, D. J. (2007). A validation of the 7.5% CO2 model of GAD using paroxetine and lorazepam in healthy volunteers. Journal of Psychopharmacology, 21(1), 42-49. https://doi.org/10.1177/0269881106063889

The inhalation of 7.5% carbon dioxide (CO2) in healthy subjects produces an increase in blood pressure and heart rate, and increased feelings of anxiety, fear and tension (Bailey et al. 2005). As this state is similar to that of general anxiety rathe... Read More about A validation of the 7.5% CO2 model of GAD using paroxetine and lorazepam in healthy volunteers.