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Effect of formulation variables on oral grittiness and preferences of multiparticulate formulations in adult volunteers (2016)
Journal Article
Lopez, F. L., Bowles, A., Gul, M. O., Clapham, D., Ernest, T. B., & Tuleu, C. (2016). Effect of formulation variables on oral grittiness and preferences of multiparticulate formulations in adult volunteers. European Journal of Pharmaceutical Sciences, 92, 156-162. https://doi.org/10.1016/j.ejps.2016.07.006

© 2016 The Authors Multiparticulate formulations are composed of multiple solid dosage units which can be administered directly to the mouth or sprinkled on food. Oral grittiness (i.e. rough mouthfeel) may arise from the presence of particles in the... Read More about Effect of formulation variables on oral grittiness and preferences of multiparticulate formulations in adult volunteers.

Specific aspects of gastro-intestinal transit in children for drug delivery design (2010)
Journal Article
Bowles, A., Keane, J., Ernest, T., Clapham, D., & Tuleu, C. (2010). Specific aspects of gastro-intestinal transit in children for drug delivery design. International Journal of Pharmaceutics, 395(1-2), 37-43. https://doi.org/10.1016/j.ijpharm.2010.04.048

This mini-review discusses relevant aspects of gastro-intestinal transit in different ages of paediatric patients with an attempt to highlight factors which should be considered in oral dosage form design, in particular multi-particulate dosage forms... Read More about Specific aspects of gastro-intestinal transit in children for drug delivery design.