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Proto–neural networks from thermal proteins (2024)
Journal Article
Mougkogiannis, P., & Adamatzky, A. (in press). Proto–neural networks from thermal proteins. Biochemical and Biophysical Research Communications, 149725. https://doi.org/10.1016/j.bbrc.2024.149725

Proteinoids are synthetic polymers that have structural similarities to natural proteins, and their formation is achieved through the application of heat to amino acid combinations in a dehydrated environment. The thermal proteins, initially synthesi... Read More about Proto–neural networks from thermal proteins.

Proto-neurons from abiotic polypeptides (2024)
Journal Article
Mougkogiannis, P., & Adamatzky, A. (2024). Proto-neurons from abiotic polypeptides. Encyclopedia, 4(1), 512-543. https://doi.org/10.3390/encyclopedia4010034

To understand the origins of life, we must first gain a grasp of the unresolved emergence of the first informational polymers and cell-like assemblies that developed into living systems. Heating amino acid mixtures to their boiling point produces the... Read More about Proto-neurons from abiotic polypeptides.

On interaction of proteinoids with simulated neural networks (2024)
Journal Article
Mougkogiannis, P., & Adamatzky, A. (2024). On interaction of proteinoids with simulated neural networks. BioSystems, 237, Article 105175. https://doi.org/10.1016/j.biosystems.2024.105175

Proteinoid-neuron networks combine biological neurons with spiking proteinoid microspheres, which are generated by thermal condensation of amino acids. Complex and dynamic spiking patterns in response to varied stimuli make these networks suitable fo... Read More about On interaction of proteinoids with simulated neural networks.

Electrical spiking activity of proteinoids-ZnO colloids (2024)
Journal Article
Mougkogiannis, P., Raeisi Kheirabadi, N., Cholerio, A., & Adamatzky, A. (2024). Electrical spiking activity of proteinoids-ZnO colloids. Neuromorphic Computing and Engineering, 4(1), Article 014007. https://doi.org/10.1088/2634-4386/ad2afb

We are studying the remarkable electrical properties of Proteinoids-ZnO microspheres with the aim of exploring their potential for a new form of computing. Our research has revealed that these microspheres exhibit behavior similar to neurons, generat... Read More about Electrical spiking activity of proteinoids-ZnO colloids.

Recognition of sounds by ensembles of proteinoids (2024)
Journal Article
Mougkogiannis, P., & Adamatzky, A. (2024). Recognition of sounds by ensembles of proteinoids. Materials Today Bio, 25, Article 100989. https://doi.org/10.1016/j.mtbio.2024.100989

Proteinoids are artificial polymers that imitate certain characteristics of natural proteins, including self-organization, catalytic activity, and responsiveness to external stimuli. This paper examines the acoustic response properties of proteinoids... Read More about Recognition of sounds by ensembles of proteinoids.

Pavlovian reflex in colloids (2024)
Journal Article
Raeisi Kheirabadi, N., Chiolerio, A., & Adamatzky, A. (in press). Pavlovian reflex in colloids. BioNanoScience, https://doi.org/10.1007/s12668-023-01287-8

Liquid computers are devices that utilise the properties of liquid volumes or reactants to represent data and outputs. A recent development in this field is the emergence of colloid computers, which employ electromagnetic interactions among functiona... Read More about Pavlovian reflex in colloids.

Electrical properties of proteinoids for unconventional computing architectures (2023)
Conference Proceeding
Mougkogiannis, P., & Adamatzky, A. (2023). Electrical properties of proteinoids for unconventional computing architectures. In NANOARCH '23: Proceedings of the 18th ACM International Symposium on Nanoscale Architectures (1-4). https://doi.org/10.1145/3611315.3633264

Proteinoids are peptide-like molecules that arise from the combination of amino acids in pre-biotic environments. Recent studies have revealed distinctive electrical characteristics of proteinoids, such as the presence of voltage-gated ion channels,... Read More about Electrical properties of proteinoids for unconventional computing architectures.

Light-induced spiking in proteinoids yields Boolean gates (2023)
Journal Article
Mougkogiannis, P., & Adamatzky, A. (2023). Light-induced spiking in proteinoids yields Boolean gates. Materials and Design, 236, Article 112460. https://doi.org/10.1016/j.matdes.2023.112460

This study analyzes light modulation of spiking in proteinoids, thermally condensed proteins exhibiting spike dynamics. We elucidate how light induces changes in proteinoids, modulating spike frequency. Results show proteinoids' spiking can be adjust... Read More about Light-induced spiking in proteinoids yields Boolean gates.

Learning in ensembles of proteinoid microspheres (2023)
Journal Article
Mougkogiannis, P., & Adamatzky, A. (2023). Learning in ensembles of proteinoid microspheres. Royal Society Open Science, 10(10), Article 230936. https://doi.org/10.1098/rsos.230936

Proteinoids are thermal proteins which form microspheres in water in the presence of salt. Ensembles of proteinoid microspheres exhibit passive nonlinear electrical properties and active neuron-like spiking of electrical potential. We propose that va... Read More about Learning in ensembles of proteinoid microspheres.

Logical gates in ensembles of proteinoid microspheres (2023)
Journal Article
Mougkogiannis, P., & Adamatzky, A. (2023). Logical gates in ensembles of proteinoid microspheres. PLoS ONE, 18(9), Article e0289433. https://doi.org/10.1371/journal.pone.0289433

Proteinoids are thermal proteins which swell into microspheres in aqueous solution. Ensembles of proteinoids produce electrical spiking activity similar to that of neurons. We introduce a novel method for implementing logical gates in the ensembles o... Read More about Logical gates in ensembles of proteinoid microspheres.

Proteinoid microspheres as protoneural networks (2023)
Journal Article
Mougkogiannis, P., & Adamatzky, A. (2023). Proteinoid microspheres as protoneural networks. ACS Omega, 8(38), 35417–35426. https://doi.org/10.1021/acsomega.3c05670

Proteinoids, also known as thermal proteins, possess a fascinating ability to generate microspheres that exhibit electrical spikes resembling the action potentials of neurons. These spiking microspheres, referred to as protoneurons, hold the potentia... Read More about Proteinoid microspheres as protoneural networks.

Light induced spiking of proteinoids (2023)
Journal Article
Mougkogiannis, P., & Adamatzky, A. (2023). Light induced spiking of proteinoids. BioSystems, 232, Article 105015. https://doi.org/10.1016/j.biosystems.2023.105015

Proteinoids, or thermal proteins, are produced by heating amino acids to their melting point and initiating polymerisation to produce polymeric chains. In aqueous solutions proteinoids swell into hollow microspheres. These microspheres produce endoge... Read More about Light induced spiking of proteinoids.

Learning in colloids: Synapse-like ZnO + DMSO colloid (2023)
Journal Article
Kheirabadi, N. R., Chiolerio, A., Phillips, N., & Adamatzky, A. (2023). Learning in colloids: Synapse-like ZnO + DMSO colloid. Neurocomputing, 557, Article 126710. https://doi.org/10.1016/j.neucom.2023.126710

Colloids subjected to electrical stimuli exhibit a reconfiguration that might be used to store information and potentially compute. In a colloidal suspension of ZnO nanoparticles in DMSO, we investigated the learning, memorization, time and stimulati... Read More about Learning in colloids: Synapse-like ZnO + DMSO colloid.

Multiscalar electrical spiking in Schizophyllum commune (2023)
Journal Article
Adamatzky, A., Schunselaar, E., Wösten, H. A. B., & Ayres, P. (2023). Multiscalar electrical spiking in Schizophyllum commune. Scientific Reports, 13(1), Article 12808. https://doi.org/10.1038/s41598-023-40163-z

Growing colonies of the split-gill fungus Schizophyllum commune show action potential-like spikes of extracellular electrical potential. We analysed several days of electrical activity recording of the fungus and discovered three families of oscillat... Read More about Multiscalar electrical spiking in Schizophyllum commune.

No ultrasounds detected from fungi when dehydrated (2023)
Journal Article
Phillips, N., Remedios, S. W., Nikolaidou, A., Baracskai, Z., & Adamatzky, A. (2023). No ultrasounds detected from fungi when dehydrated. Ultrasonics, 135, Article 107111. https://doi.org/10.1016/j.ultras.2023.107111

Many organisms (including certain plant species) can be observed to emit sounds, potentially signifying threat alerts. Sensitivity to such sounds and vibrations may also play an important role in the lives of fungi. In this work, we explore the poten... Read More about No ultrasounds detected from fungi when dehydrated.

Author correction: Kombucha electronics: Electronic circuits on kombucha mats (2023)
Journal Article
Adamatzky, A., Tarabella, G., Phillips, N., Chiolerio, A., D’Angelo, P., Nikolaidou, A., & Sirakoulis, G. C. (2023). Author correction: Kombucha electronics: Electronic circuits on kombucha mats. Scientific Reports, 13(1), Article 11204. https://doi.org/10.1038/s41598-023-38161-2

Correction to: Scientific Reports, published online 09 June 2023 The original version of this Article contained an error in the spelling of the author Pasquale D’Angelo which was incorrectly given as Passquale D’Angelo. The original Article has been... Read More about Author correction: Kombucha electronics: Electronic circuits on kombucha mats.

Kombucha electronics: Electronic circuits on kombucha mats (2023)
Journal Article
Adamatzky, A., Tarabella, G., Phillips, N., Chiolerio, A., D’Angelo, P., Nikolaidou, A., & Sirakoulis, G. C. (2023). Kombucha electronics: Electronic circuits on kombucha mats. Scientific Reports, 13(1), 9367. https://doi.org/10.1038/s41598-023-36244-8

A kombucha is a tea and sugar fermented by over sixty kinds of yeasts and bacteria. This symbiotic community produces kombucha mats, which are cellulose-based hydrogels. The kombucha mats can be used as an alternative to animal leather in industry an... Read More about Kombucha electronics: Electronic circuits on kombucha mats.

Propagation of electrical signals by fungi (2023)
Journal Article
Mayne, R., Roberts, N., Phillips, N., Weerasekera, R., & Adamatzky, A. (2023). Propagation of electrical signals by fungi. BioSystems, 229, Article 104933. https://doi.org/10.1016/j.biosystems.2023.104933

Living fungal mycelium networks are proven to have properties of memristors, capacitors and various sensors. To further progress our designs in fungal electronics we need to evaluate how electrical signals can be propagated through mycelium networks.... Read More about Propagation of electrical signals by fungi.