The effects of resistance training on quality of life in cancer: A systematic literature review and meta-analysis

Cramp, Fiona (Alice); James, Abigail; Lambert, Jessica

Abstract

Purpose The purpose of this study was to carry out a systematic review and meta-analysis to evaluate the effect of resistance training upon quality of life (QoL) in cancer. Methods Search strategy: A wide range of electronic databases were searched from inception to October 2009 using relevant key words. Reference lists of all studies identified for inclusion and relevant reviews were also searched. Relevant journals were hand searched and experts in the field contacted. Selection criteria: Randomized controlled trials that investigated the specific effect of resistance training on QoL in adult cancer survivors were included. Data collection and analysis: Two review authors independently assessed methodological quality and extracted data based upon predefined criteria. A meta-analysis was performed for QoL using a random effects model. Results Six studies were identified for inclusion. Two studies demonstrated a significantly beneficial effect of resistance training on QoL compared to usual care. Posttest means ± standard deviations were available for all comparisons providing data for 278 participants who received a resistance training intervention and 270 control participants. The results of the meta-analysis demonstrated that, at the end of the intervention period, resistance training was statistically more effective than the control intervention (SMD -0.17, 95% CIs -0.34 to -0.00). Overall, there was heterogeneity between studies in relation to tumor type, stage of cancer treatment, type of cancer treatment, and duration of the intervention. Conclusions Existing evidence suggests that strength training programs for cancer survivors have marginal benefit. Further, fully powered studies are required to determine the optimal type, intensity, and timing of resistance training. © Springer-Verlag 2009.

Citation

Cramp, F. (., James, A., & Lambert, J. (2010). The effects of resistance training on quality of life in cancer: A systematic literature review and meta-analysis. Supportive Care in Cancer, 18(11), 1367-1376. https://doi.org/10.1007/s00520-010-0904-z

• Journal Article Type: Review
• Publication Date: Nov 1, 2010
• Deposit Date: Dec 13, 2010
• Publicly Available Date: May 16, 2016
• Journal: Supportive Care in Cancer
• Print ISSN: 0941-4355
• Electronic ISSN: 1433-7339
• Publisher: Springer (part of Springer Nature)
• Peer Reviewed: Peer Reviewed
• Volume: 18
• Issue: 11
• Pages: 1367-1376
• DOI: https://doi.org/10.1007/s00520-010-0904-z
• Keywords: cancer, fatigue, quality of life, resistance training, strength training, systematic review, meta-analysis
• Public URL: https://uwe-repository.worktribe.com/output/984195
• Publisher URL: http://dx.doi.org/10.1007/s00520-010-0904-z
• Additional Information: Additional Information : The original publication is available at www.springerlink.com