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Cancer-related fatigue and its impact on functioning

Barsevick, Andrea; Cramp, Fiona; Goedendorp, Martine; Mitchell, Sandra A.; Cramp, Fiona (Alice); Minton, Ollie; Berger, Ann; Stone, Patrick C.

Authors

Andrea Barsevick

Fiona Cramp

Martine Goedendorp

Sandra A. Mitchell

Fiona Cramp Fiona.Cramp@uwe.ac.uk
Professor in Long Term Conditions

Ollie Minton

Ann Berger

Patrick C. Stone



Abstract

This article presents the contrasting European and American perspectives on cancer-related fatigue (CRF) and its impact on functioning in cancer survivors. The content is presented in 3 sections: state of the art, intervention studies, and future areas of research, followed by a discussion. Gaps identified include a lack of understanding of the etiology, definition, and measurement of CRF. Models to guide the study of CRF, selection of biomarkers, and design of interventions are needed. There is overlap between Europe and the United States concerning the future directions for research and collaboration related to CRF. The authors suggest the need for international consensus regarding the defining features of CRF in cancer survivors to identify phenotypes, a harmonized measurement of CRF outcomes using instruments that have demonstrated measurement equivalence across languages and cultures, and interventions (including exercise, rehabilitation, and psychoeducational) that have been manualized to permit intervention fidelity across diverse contexts. Coordinated intercontinental efforts would increase understanding of the biological, psychological, and social mechanisms underlying CRF and assist in the design of future intervention studies as well as revisions to clinical guidelines. © 2013 American Cancer Society.

Citation

Mitchell, S. A., Goedendorp, M., Cramp, F., Barsevick, A., Minton, O., Cramp, F. (., …Stone, P. C. (2013). Cancer-related fatigue and its impact on functioning. Cancer, 119(SUPPL11), 2124-2130. https://doi.org/10.1002/cncr.28058

Journal Article Type Article
Publication Date Jun 1, 2013
Journal Cancer
Print ISSN 0008-543X
Electronic ISSN 1097-0142
Publisher Wiley
Peer Reviewed Peer Reviewed
Volume 119
Issue SUPPL11
Pages 2124-2130
DOI https://doi.org/10.1002/cncr.28058
Keywords cancer, fatigue
Public URL https://uwe-repository.worktribe.com/output/931495
Publisher URL http://dx.doi.org/10.1002/cncr.28058