Paul R. Clarke
A mitotic role for BRCA1/BARD1 in tumor suppression?
Clarke, Paul R.; Sanderson, Helen S.
Abstract
The tumor-suppressor protein BRCA1 is thought to act by preserving genomic integrity. In this issue of Cell, Joukov et al. (2006) demonstrate that the BRCA1/BARD1 heterodimer participates in mitotic spindle assembly, a process conducted by the GTPase Ran. Loss of this mitotic function might contribute to tumorigenesis. © 2006 Elsevier Inc. All rights reserved.
Citation
Clarke, P. R., & Sanderson, H. S. (2006). A mitotic role for BRCA1/BARD1 in tumor suppression?. Cell, 127(3), 453-455. https://doi.org/10.1016/j.cell.2006.10.020
Journal Article Type | Commentary |
---|---|
Acceptance Date | Aug 3, 2006 |
Online Publication Date | Nov 3, 2006 |
Publication Date | Nov 3, 2006 |
Deposit Date | Jun 22, 2021 |
Journal | Cell |
Print ISSN | 0092-8674 |
Publisher | Elsevier (Cell Press) |
Peer Reviewed | Not Peer Reviewed |
Volume | 127 |
Issue | 3 |
Pages | 453-455 |
DOI | https://doi.org/10.1016/j.cell.2006.10.020 |
Public URL | https://uwe-repository.worktribe.com/output/7483603 |
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