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Factors that affect quality of life among people living with HIV attending an urban clinic in Uganda: A cohort study

Katamba, Achilles; Mutabazi-Mwesigire, Doris; Martin, Faith; Seeley, Janet; Wu, Albert W.

Authors

Achilles Katamba

Doris Mutabazi-Mwesigire

Faith Martin Faith.Martin@uwe.ac.uk
Wallscourt Fellow in Wellbeing and Mental Wealth

Janet Seeley

Albert W. Wu



Abstract

© 2015 Mutabazi-Mwesigire et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Introduction: With the availability of antiretroviral therapy (ART) and primary general care for people living with HIV (PLHIV) in resource limited settings, PLHIV are living longer, and HIV has been transformed into a chronic illness. People are diagnosed and started on treatment when they are relatively well. Although ART results in clinical improvement, the ultimate goal of treatment is full physical functioning and general well-being, with a focus on quality of life rather than clinical outcomes. However, there has been little research on the relationship of specific factors to quality of life in PLHIV. The objective of this study was to investigate factors associated with quality of life among PLHIV in Uganda receiving basic care and those on ART. Methods: We enrolled 1274 patients attending an HIV outpatient clinic into a prospective cohort study. Of these, 640 received ART. All were followed up at 3 and 6 months. Health related quality of life was assessed with the MOS-HIV Health Survey and the Global Person Generated Index (GPGI). Multivariate linear regression and logistic regression with generalized estimating equations were used to examine the relationship of social behavioral and disease factors with Physical Health Summary (PHS) score, Mental Health Summary (MHS) score, and GPGI. Results: Among PLHIV receiving basic care, PHS was associated with: sex (p=0.045) - females had lower PHS; age in years at enrollment (p=0.0001) - older patients had lower PHS; and depression (p

Citation

Katamba, A., Mutabazi-Mwesigire, D., Martin, F., Seeley, J., & Wu, A. W. (2015). Factors that affect quality of life among people living with HIV attending an urban clinic in Uganda: A cohort study. PLoS ONE, 10(6), e0126810. https://doi.org/10.1371/journal.pone.0126810

Journal Article Type Article
Acceptance Date Apr 8, 2015
Online Publication Date Jun 3, 2015
Publication Date Jun 3, 2015
Deposit Date Sep 18, 2019
Publicly Available Date Sep 18, 2019
Journal PLoS ONE
Electronic ISSN 1932-6203
Publisher Public Library of Science
Peer Reviewed Peer Reviewed
Volume 10
Issue 6
Pages e0126810
DOI https://doi.org/10.1371/journal.pone.0126810
Keywords General Biochemistry, Genetics and Molecular Biology; General Agricultural and Biological Sciences; General Medicine
Public URL https://uwe-repository.worktribe.com/output/3069230

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Factors That Affect Quality of Life among People Living with HIV Attending an Urban Clinic in Uganda: A Cohort Study (763 Kb)
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Copyright Statement
© 2015 Mutabazi-Mwesigire et al. This is
an open access article distributed under the terms of
the Creative Commons Attribution License, which
permits unrestricted use, distribution, and
reproduction in any medium, provided the original
author and source are credited.



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