Andrew Smith
Effects of repeated doses of caffeine on mood and performance of alert and fatigued volunteers
Smith, Andrew; Sutherland, David; Christopher, Gary
Authors
David Sutherland
Gary Christopher Gary.Christopher@uwe.ac.uk
Occasional Associate Lecturer - CHSS - AHP
Abstract
Evidence for behavioural effects of caffeine is well documented in the literature. It is associated with increased subjective alertness, improved reaction time and enhanced encoding of new information. These effects are most prominent in low arousal situations. However, there is an ongoing debate as to whether such changes are in fact improvements or merely a reversal of the negative effects of a period of caffeine withdrawal (e.g. overnight abstinence). To avoid such a confound this study included multiple doses of caffeine which were administered under double-blind conditions to participants who had ingested their normal daily quota of caffeine. In the present study participants were fatigued by carrying out a prolonged testing schedule in the evening. Sixty volunteers, all regular caffeine consumers, took part in the study. They attended for three sessions on separate days. They were instructed to consume normal amounts of caffeinated beverages. Consumption was measured by a diary and saliva samples were taken and caffeine assays conducted. A baseline test session was carried out at 18.00 h and following this a double blind placebo controlled caffeine challenge (1.5 mg/kg) conducted. The test battery was repeated twice approximately 30 minutes after the caffeine challenge. Following this another drink was administered and the test battery repeated twice more. On one test session volunteers had placebo in both drinks, in another they had caffeine in both drinks and another caffeine in the first and placebo in the second. Order of conditions was balanced across subjects. The results showed that caffeine led to a more positive mood and improved performance on a number of tasks. Different effects of caffeine were seen depending on the person's level of arousal. Linear effects of caffeine dose were also observed. This is evidence against the argument that behavioural changes due to caffeine are merely the reversal of negative effects of a long period of caffeine abstinence. The findings are discussed in relation to both noradrenergic and cholinergic neurotransmitter systems. © 2005 British Association for Psychopharmacology.
Citation
Smith, A., Sutherland, D., & Christopher, G. (2005). Effects of repeated doses of caffeine on mood and performance of alert and fatigued volunteers. Journal of Psychopharmacology, 19(6), 620-626. https://doi.org/10.1177/0269881105056534
Journal Article Type | Article |
---|---|
Publication Date | Nov 1, 2005 |
Journal | Journal of Psychopharmacology |
Print ISSN | 0269-8811 |
Publisher | SAGE Publications |
Peer Reviewed | Peer Reviewed |
Volume | 19 |
Issue | 6 |
Pages | 620-626 |
DOI | https://doi.org/10.1177/0269881105056534 |
Keywords | arousal, caffeine, psychomotor performance, mood, psychopharmacology |
Public URL | https://uwe-repository.worktribe.com/output/1056210 |
Publisher URL | http://dx.doi.org/10.1177/0269881105056534 |
You might also like
The mnemic neglect effect and information about dementia: Age differences in recall
(2020)
Journal Article
The development and validation of the Threat of Dementia Scale
(2020)
Journal Article
Can colouring improve the mood and concentration of older adults? Developing a research study
(2019)
Presentation / Conference
The effects of clinical task interruptions on subsequent performance of a medication pre-administration task
(2019)
Conference Proceeding
Downloadable Citations
About UWE Bristol Research Repository
Administrator e-mail: repository@uwe.ac.uk
This application uses the following open-source libraries:
SheetJS Community Edition
Apache License Version 2.0 (http://www.apache.org/licenses/)
PDF.js
Apache License Version 2.0 (http://www.apache.org/licenses/)
Font Awesome
SIL OFL 1.1 (http://scripts.sil.org/OFL)
MIT License (http://opensource.org/licenses/mit-license.html)
CC BY 3.0 ( http://creativecommons.org/licenses/by/3.0/)
Powered by Worktribe © 2024
Advanced Search