@article { , title = {Alternative splicing in the hippo pathway-implications for disease and potential therapeutic targets}, abstract = {© 2018 by the authors. Licensee MDPI, Basel, Switzerland. Alternative splicing is a well-studied gene regulatory mechanism that produces biological diversity by allowing the production of multiple protein isoforms from a single gene. An involvement of alternative splicing in the key biological signalling Hippo pathway is emerging and offers new therapeutic avenues. This review discusses examples of alternative splicing in the Hippo pathway, how deregulation of these processes may contribute to disease and whether these processes offer new potential therapeutic targets.}, doi = {10.3390/genes9030161}, eissn = {2073-4425}, issue = {3}, journal = {Genes}, pages = {161}, publicationstatus = {Published}, publisher = {MDPI}, url = {https://uwe-repository.worktribe.com/output/875606}, volume = {9}, keyword = {Centre for Research in Biosciences, hippo pathway, alternative splicing, yes-associated protein, splice-switching oligonucleotides, gene therapy}, year = {2018}, author = {Porazinski, Sean and Ladomery, Michael} }