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Promoting access to haemostasis testing in resource-scarce and emergency settings using paper-based lateral flow diagnostic screening assays for coagulation disorders (2023)
Thesis
Saidykhan, J. Promoting access to haemostasis testing in resource-scarce and emergency settings using paper-based lateral flow diagnostic screening assays for coagulation disorders. (Thesis). University of the West of England. Retrieved from https://uwe-repository.worktribe.com/output/10774108

Haemostatic disorders cause excessive bleeding and clotting and result in high morbidity and mortality worldwide, but especially in low-income areas which often lack suitable facilities and expertise for affordable diagnosis and treatment. Simple and... Read More about Promoting access to haemostasis testing in resource-scarce and emergency settings using paper-based lateral flow diagnostic screening assays for coagulation disorders.

Art and the schizophrenic spectrum (2023)
Book Chapter
Holt, N. (2023). Art and the schizophrenic spectrum. In P. Crawford, & P. Kadetz (Eds.), Palgrave Encyclopedia of the Health Humanities. (1). Palgrave Macmillan (part of Springer Nature). https://doi.org/10.1007/978-3-030-26825-1_20-1

There is an ‘art and health’ paradox in the literature on the schizophrenic spectrum, since features of the schizophrenic spectrum have been argued to facilitate artistic creativity (e.g., by enabling novel perspectives, images or insights), suggesti... Read More about Art and the schizophrenic spectrum.

HOCl vs OCl−: clarification on chlorine-based disinfectants used within clinical settings (2023)
Journal Article
Mehendale, F. V., Mehendale, F., Homyer, K. M., Clayton, G., Reynolds, D. M., Homyer, K., & Reynolds, D. (2023). HOCl vs OCl−: clarification on chlorine-based disinfectants used within clinical settings. Journal of Global Health Reports, 7, Article e2023052. https://doi.org/10.29392/001c.84488

Disinfection is a mainstay of infection prevention, the importance of which was highlighted throughout the SARS-CoV-2 pandemic. There is frequent misuse of terminology surrounding chlorine solutions in the literature. This leads not only to confusion... Read More about HOCl vs OCl−: clarification on chlorine-based disinfectants used within clinical settings.

Development of a novel dual-enzyme screen-printed amperometric biosensor for the analysis of esterified fatty acids (2023)
Journal Article
Smart, A., Crew, A., Doran, O., & Hart, J. (2023). Development of a novel dual-enzyme screen-printed amperometric biosensor for the analysis of esterified fatty acids. Journal of Food Composition and Analysis, 122, Article 105488. https://doi.org/10.1016/j.jfca.2023.105488

This paper describes, for the first time, the development of a novel trilinolein biosensor based on the immobilisation of lipase and lipoxygenase (LOX) onto a cobalt phthalocyanine screen-printed carbon electrode (CoPC-SPCE) in conjunction with amper... Read More about Development of a novel dual-enzyme screen-printed amperometric biosensor for the analysis of esterified fatty acids.

Amplifying the voices of neurodivergent students in relation to higher education assessment at UWE Bristol (2023)
Report
Chicken, S., Fogg Rogers, L., Hobbs, L., Hunt-Fraisse, T., & Lewis, D. (2023). Amplifying the voices of neurodivergent students in relation to higher education assessment at UWE Bristol. UWE Bristol

This paper reports on a study funded by the UWE Pedagogical Project fund in 2021-2022, which aimed to amplify the voices of neurodivergent (referred to as ‘ND’) students in relation to lived experiences of Higher Education (HE) assessment practices w... Read More about Amplifying the voices of neurodivergent students in relation to higher education assessment at UWE Bristol.

Promoting dietary changes for achieving health and sustainability targets (2023)
Journal Article
Sanderson Bellamy, A., Furness, E., Mills, S., Clear, A., Finnigan, S. M., Meador, E., …Sharp, R. T. (2023). Promoting dietary changes for achieving health and sustainability targets. Frontiers in Sustainable Food Systems, 7, Article 1160627. https://doi.org/10.3389/fsufs.2023.1160627

Globally, about 21–37% of total greenhouse gas (GHG) emissions are attributable to food systems. Dietary-related non-communicable diseases have increased significantly from 1990–2019 at a global scale. To achieve carbon emissions targets, increase re... Read More about Promoting dietary changes for achieving health and sustainability targets.

Genomic analysis of two novel bacteriophages infecting acinetobacter beijerinckii and halotolerans species (2023)
Journal Article
Gomes, M., Domingues, R., Turner, D., & Oliveira, H. (2023). Genomic analysis of two novel bacteriophages infecting acinetobacter beijerinckii and halotolerans species. Viruses, 15(3), 643. https://doi.org/10.3390/v15030643

Bacteriophages are the most diverse genetic entities on Earth. In this study, two novel bacteriophages, nACB1 (Podoviridae morphotype) and nACB2 (Myoviridae morphotype), which infect Acinetobacter beijerinckii and Acinetobacter halotolerans, respecti... Read More about Genomic analysis of two novel bacteriophages infecting acinetobacter beijerinckii and halotolerans species.

Variations in bacteriological and physicochemical water quality characteristics of Asata River, Enugu, Nigeria (2023)
Journal Article
Ozochi, C., Nwankwo, C., Enemuor, S., Chidebelu, P., Adukwu, E., & Chigor, V. (2023). Variations in bacteriological and physicochemical water quality characteristics of Asata River, Enugu, Nigeria. Microbiology Journal, 13(1), 1-10. https://doi.org/10.3923/mj.2023.1.10

Background and Objective: Globally, river water remains an important source of water for drinking, domestic and other uses. This study aimed to assess the bacteriological and physicochemical properties of Asata River water. Materials and Methods: A... Read More about Variations in bacteriological and physicochemical water quality characteristics of Asata River, Enugu, Nigeria.

Systematic review of surveillance systems for AMR in Africa (2022)
Journal Article
Okolie, O., Igwe, U., Ismail, S., Uzairue, L., & Adukwu, E. C. (2022). Systematic review of surveillance systems for AMR in Africa. Journal of Antimicrobial Chemotherapy, 78(1), 31-51. https://doi.org/10.1093/jac/dkac342

AIMS: Surveillance is a useful tool for tracking antimicrobial resistance (AMR) trends, patterns, therapeutic and policy interventions. Proper correlation of surveillance data gives meaningful insight into the underlying epidemiology and facilitates... Read More about Systematic review of surveillance systems for AMR in Africa.

Benefits of realist evaluation for rapidly changing health service delivery (2022)
Journal Article
Jagosh, J., Stott, H., Halls, S., Thomas, R., Liddiard, C., Cupples, M., …Walsh, N. E. (2022). Benefits of realist evaluation for rapidly changing health service delivery. BMJ Open, 12(7), e060347. https://doi.org/10.1136/bmjopen-2021-060347

Realist evaluation is a methodology that addresses the questions: 'what works, for whom, in which circumstances, and how?'. In this approach, programme theories are developed and tested against available evidence. However, when complex interventions... Read More about Benefits of realist evaluation for rapidly changing health service delivery.

Eliminating transition state calculations for faster and more accurate reactivity prediction in Sulfa-Michael additions relevant to human health and the environment (2022)
Journal Article
Townsend, P. A., Farrar, E. H., & Grayson, M. N. (2022). Eliminating transition state calculations for faster and more accurate reactivity prediction in Sulfa-Michael additions relevant to human health and the environment. ACS Omega, 7(30), 26945-26951. https://doi.org/10.1021/acsomega.2c03739

Fast and accurate computational approaches to predicting reactivity in sulfa-Michael additions are required for high-throughput screening in toxicology (e.g., predicting excess aquatic toxicity and skin sensitization), chemical synthesis, covalent dr... Read More about Eliminating transition state calculations for faster and more accurate reactivity prediction in Sulfa-Michael additions relevant to human health and the environment.

A novel in vitro 3D model of the human bone marrow to bridge the gap between in vitro and in vivo genotoxicity testing (2022)
Journal Article
Vernon, A. R., Pemberton, R. M., & Morse, H. (2022). A novel in vitro 3D model of the human bone marrow to bridge the gap between in vitro and in vivo genotoxicity testing. Mutagenesis, 37(2), 112-129. https://doi.org/10.1093/mutage/geac009

The regulatory 2D in vitro micronucleus (MN) assay is part of a battery of tests, used to test for genotoxicity of new and existing compounds before they are assessed in vivo (ICH S2). The 2D MN assay consists of a monolayer of cells, whereas the in... Read More about A novel in vitro 3D model of the human bone marrow to bridge the gap between in vitro and in vivo genotoxicity testing.

A reappraisal of public engagement in Oxford during the pandemic: Three case studies (2022)
Journal Article
Farrell, M., & Wilkinson, C. (2022). A reappraisal of public engagement in Oxford during the pandemic: Three case studies. Research Involvement and Engagement, 8(1), Article 10. https://doi.org/10.1186/s40900-022-00343-z

Background: The COVID-19 pandemic has resulted in the majority of public engagement with research work moving online. This shift to online engagement is likely to affect inclusivity and diversity in such events and this requires further consideration... Read More about A reappraisal of public engagement in Oxford during the pandemic: Three case studies.

Access to chronic pain services for adults from Minority Ethnic groups in the United Kingdom: A scoping review protocol (2022)
Journal Article
Leach, E., Ndosi, M., Ambler, H., Park, S., & Lewis, J. (2022). Access to chronic pain services for adults from Minority Ethnic groups in the United Kingdom: A scoping review protocol. Musculoskeletal Care, 20(4), 731-741. https://doi.org/10.1002/msc.1629

Background: Chronic pain services in the United Kingdom are required to provide services which meet the diverse needs of patients, but little is known about the access and use of these services by Minority Ethnic groups. This protocol describes a sco... Read More about Access to chronic pain services for adults from Minority Ethnic groups in the United Kingdom: A scoping review protocol.

Early determinants of mortality in hospitalized COVID-19 patients in the Eastern Province of Saudi Arabia (2022)
Journal Article
Ansari, K. A., Alwazzeh, M. J., Alkuwaiti, F. A., Farooqi, F. A., Al Khathlan, N., Almutawah, H., …Alkuwaiti, E. (2022). Early determinants of mortality in hospitalized COVID-19 patients in the Eastern Province of Saudi Arabia. International Journal of General Medicine, 15(15), 1689-1701. https://doi.org/10.2147/ijgm.s349598

Purpose: This study investigated the clinical determinants of mortality in hospitalized patients infected with COVID-19. Patients and Methods: A retrospective multicenter large cohort of COVID-19 patients hospitalized between March 2020 and February... Read More about Early determinants of mortality in hospitalized COVID-19 patients in the Eastern Province of Saudi Arabia.

Genomic diversity of bacteriophages infecting the genus acinetobacter (2022)
Journal Article
Oliveira, H., Domingues, R., Evans, B., Sutton, J. M., Adriaenssens, E. M., & Turner, D. (2022). Genomic diversity of bacteriophages infecting the genus acinetobacter. Viruses, 14(2), Article 181. https://doi.org/10.3390/v14020181

The number of sequenced Acinetobacter phage genomes in the International Nucleotide Sequence Database Collaboration has increased significantly in recent years, from 37 in 2017 to a total of 139 as of January 2021 with genome sizes ranging from 31 to... Read More about Genomic diversity of bacteriophages infecting the genus acinetobacter.

Peoples’ experiences of painful diabetic neuropathy: A qualitative interview study (2021)
Journal Article
McCabe, C., Cramp, F., Gauntlett-Gilbert, J., & Davies, B. (2021). Peoples’ experiences of painful diabetic neuropathy: A qualitative interview study. Pain and Rehabilitation, 50, 14-21

Objective Painful diabetic neuropathy (PDN) is a common complication of diabetes. This study explored the experience and impact of living with PDN. Design People with PDN were recruited through local NHS clinics and by national advertisement in di... Read More about Peoples’ experiences of painful diabetic neuropathy: A qualitative interview study.

Primary mesenchymal stromal cells in co-culture with leukaemic HL-60 cells are sensitised to cytarabine-induced genotoxicity, while leukaemic cells are protected (2021)
Journal Article
Gynn, L. E., Anderson, E., Robinson, G., Wexler, S. A., Upstill-Goddard, G., Cox, C., & May, J. E. (2021). Primary mesenchymal stromal cells in co-culture with leukaemic HL-60 cells are sensitised to cytarabine-induced genotoxicity, while leukaemic cells are protected. Mutagenesis, 36(6), 419-428. https://doi.org/10.1093/mutage/geab033

Tumour microenvironments are hallmarked in many cancer types. In haematological malignancies, bone marrow (BM) mesenchymal stromal cells (MSC) protect malignant cells from drug-induced cytotoxicity. However, less is known about malignant impact on su... Read More about Primary mesenchymal stromal cells in co-culture with leukaemic HL-60 cells are sensitised to cytarabine-induced genotoxicity, while leukaemic cells are protected.

CDC2-like (CLK) protein kinase inhibition as a novel targeted therapeutic strategy in prostate cancer (2021)
Journal Article
Uzor, S., Porazinski, S., Li, L., Clark, B., Ajiro, M., Iida, K., …Ladomery, M. (2021). CDC2-like (CLK) protein kinase inhibition as a novel targeted therapeutic strategy in prostate cancer. Scientific Reports, 11(1), Article 7963. https://doi.org/10.1038/s41598-021-86908-6

Dysregulation of alternative splicing is a feature of cancer, both in aetiology and progression. It occurs because of mutations in splice sites or sites that regulate splicing, or because of the altered expression and activity of splice factors and o... Read More about CDC2-like (CLK) protein kinase inhibition as a novel targeted therapeutic strategy in prostate cancer.